{"id":"W4313372062","doi":"10.4049/jimmunol.204.supp.153.12","title":"RIP Kinase death pathways regulate B cell homeostasis and splenic architecture","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Mary's University","funders":"","keywords":"RIPK1; Necroptosis; Programmed cell death; Cell biology; Biology; Kinase; Caspase 8; Caspase; Apoptosis; Immune system; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014187,0.0003142498,0.0001121348,0.0003363153,0.0001740969,0.0003532678,0.0002178443,0.0002232709,0.001704223],"category_scores_gemma":[0.0001100488,0.0001327733,0.0001674321,0.0001079459,0.0002535985,0.0002697804,0.0002556652,0.0005351313,0.0007479125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003293313,"about_ca_system_score_gemma":0.0001383952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002021898,"about_ca_topic_score_gemma":0.0002184594,"domain_scores_codex":[0.999861,0.00002289624,0.000009892166,0.00003155276,0.00002297095,0.00005166035],"domain_scores_gemma":[0.9998073,0.00001154894,0.00006931461,0.00001779437,0.00002187059,0.00007220912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001493498,0.000009825682,0.0005548611,0.00001606809,0.00000258188,0.00003523924,0.000007805804,0.00004034958,0.9983535,0.0001189099,0.00003076328,0.0006807581],"study_design_scores_gemma":[0.0000352914,0.0002238423,0.01907835,0.000009652198,0.00002230426,0.0006181134,0.00006806033,0.0009846792,0.9766039,0.0002523352,0.002098315,0.000005245513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932354,0.001967405,0.002236363,0.00006663409,0.00001292042,0.00001582024,0.0004785159,0.0001491621,0.001837804],"genre_scores_gemma":[0.9961529,0.0004560411,0.001249507,0.00003474321,0.000007170596,0.00002106422,0.0003770308,0.00003304472,0.001668413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001704223,"threshold_uncertainty_score":0.005701184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01140627109482513,"score_gpt":0.2006147964308518,"score_spread":0.1892085253360266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}