{"id":"W4313381160","doi":"10.4049/jimmunol.202.supp.194.41","title":"TNF superfamily cytokines overcome immune evasion in medulloblastoma","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; BC Cancer Agency; Canada's Michael Smith Genome Sciences Centre; Hospital for Sick Children","funders":"","keywords":"Cytotoxic T cell; Tumor necrosis factor alpha; Major histocompatibility complex; Biology; Immune system; Cancer research; MHC class I; CD8; Immunotherapy; Lymphotoxin; Immunology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009837735,0.000192089,0.0002339794,0.0001710731,0.00010913,0.0001822077,0.000104044,0.0001499552,0.0007171371],"category_scores_gemma":[0.00009752346,0.00006009571,0.0001435417,0.00007728866,0.0001314043,0.0001166774,0.0001224981,0.0004981426,0.0001813085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002481082,"about_ca_system_score_gemma":0.0001690959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000924611,"about_ca_topic_score_gemma":0.001522901,"domain_scores_codex":[0.9999391,0.00001204037,0.000005504045,0.000009084351,0.00001324653,0.00002111101],"domain_scores_gemma":[0.9999372,0.00001099565,0.00001756304,0.000007287879,0.000006079282,0.00002096198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000819221,0.0001301612,0.0006830739,0.00006630809,0.00001564667,0.00021007,0.00002938859,0.0002425866,0.98884,0.0001828271,0.0002325132,0.008548194],"study_design_scores_gemma":[0.0002576623,0.004778828,0.004962501,0.00001378782,0.00005092917,0.001215535,0.00005626142,0.00160761,0.9776775,0.0001418456,0.0092328,0.000004734694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958457,0.002175443,0.0007091083,0.0001135908,0.00006767872,0.00002466014,0.0001003502,0.00006357361,0.0008998401],"genre_scores_gemma":[0.9976596,0.0006527426,0.000415624,0.00002568474,0.00001862017,0.00001082898,0.00009651368,0.000006522609,0.001113938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000924611,"threshold_uncertainty_score":0.002399027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01093664578810239,"score_gpt":0.2541883781754706,"score_spread":0.2432517323873682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}