{"id":"W4313381201","doi":"10.4049/jimmunol.202.supp.192.4","title":"Enhancement of gut barrier function by microbial metabolite, urolithin A via AhR-Nrf2 dependent pathways in IBD","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Pomegranate: compositions and health benefits","field":"Nursing","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Aryl hydrocarbon receptor; Ellagic acid; Colitis; Barrier function; Inflammation; Dysbiosis; Gut flora; Metabolite; Immune system; Ulcerative colitis; Chemistry; Immunology; Pharmacology; Biology; Biochemistry; Medicine; Cell biology; Antioxidant; Transcription factor; Polyphenol; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001016888,0.0001376639,0.0004210997,0.0002640193,0.00009240951,0.000007384614,0.0002888124,0.000124684,0.0002204841],"category_scores_gemma":[0.00002165586,0.00009910885,0.0001005815,0.000173358,0.00006512462,0.0001417071,0.00004829612,0.0005247527,0.00004034552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00014788,"about_ca_system_score_gemma":0.00007253556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003398942,"about_ca_topic_score_gemma":0.00004412505,"domain_scores_codex":[0.9981345,0.0004165342,0.0008253584,0.000107315,0.0001921439,0.0003241664],"domain_scores_gemma":[0.9987837,0.0001211123,0.0006155961,0.0002578396,0.0001762436,0.00004548214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002610209,0.0002027839,0.0004966998,0.0000221006,0.0001002521,0.000002193524,0.001087883,0.0000671574,0.9883541,0.0001556028,0.000319423,0.006581604],"study_design_scores_gemma":[0.01074116,0.006728702,0.08479329,0.0003686186,0.0004427433,0.0009455915,0.001352438,0.0003306081,0.870865,0.005045493,0.01789297,0.0004933956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981108,0.01467308,0.0008265963,0.0008777192,0.002031235,0.0002198584,0.00001900369,0.000005812673,0.0002386945],"genre_scores_gemma":[0.998659,0.0005193094,0.0001510396,0.0004762781,0.00006842998,0.000002547567,0.000004873458,0.0000148361,0.0001037554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1174891,"threshold_uncertainty_score":0.4041541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008786464400550913,"score_gpt":0.2341443227152429,"score_spread":0.225357858314692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}