{"id":"W4313381201","doi":"10.4049/jimmunol.202.supp.192.4","title":"Enhancement of gut barrier function by microbial metabolite, urolithin A via AhR-Nrf2 dependent pathways in IBD","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Pomegranate: compositions and health benefits","field":"Nursing","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Aryl hydrocarbon receptor; Ellagic acid; Colitis; Barrier function; Inflammation; Dysbiosis; Gut flora; Metabolite; Immune system; Ulcerative colitis; Chemistry; Immunology; Pharmacology; Biology; Biochemistry; Medicine; Cell biology; Antioxidant; Transcription factor; Polyphenol; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001837602,0.0002744822,0.0003660823,0.000268105,0.0001582567,0.0002014243,0.0001444695,0.0003447747,0.0017082],"category_scores_gemma":[0.00007685863,0.00009212267,0.0003800454,0.0001714906,0.000170177,0.0002778624,0.0001779366,0.0005908495,0.0002096353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001647302,"about_ca_system_score_gemma":0.0001591864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004021707,"about_ca_topic_score_gemma":0.0007105593,"domain_scores_codex":[0.9999114,0.00001828423,0.00000974078,0.00001555109,0.00001787832,0.00002705777],"domain_scores_gemma":[0.9999197,0.000006549778,0.00002503881,0.000006854218,0.00001641872,0.00002542543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007789645,0.0001124953,0.0003971719,0.0002516021,0.00002412003,0.0001118897,0.00001622975,0.00004980623,0.9955745,0.0001055682,0.00009967978,0.002478081],"study_design_scores_gemma":[0.0001534154,0.00417589,0.02414394,0.00005014068,0.0001149923,0.000731456,0.0001485884,0.0007282969,0.9621831,0.0003118136,0.00723936,0.00001892483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764104,0.01664861,0.003695299,0.0004649961,0.0001370941,0.00005842367,0.0007600969,0.000148727,0.001676362],"genre_scores_gemma":[0.9918212,0.003822917,0.001365969,0.0001539072,0.00002267456,0.00004098959,0.0004520888,0.000006545181,0.002313668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0017082,"threshold_uncertainty_score":0.005714536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008786464400550913,"score_gpt":0.2341443227152429,"score_spread":0.225357858314692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}