{"id":"W4313381922","doi":"10.4049/jimmunol.198.supp.216.12","title":"PCSK9 regulates LDL-dependent uptake of bacterial lipids by HepG2 cells through LDL receptor","year":2017,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"PCSK9; LDL receptor; Lipoteichoic acid; Antibody; Lipoprotein; Lipopolysaccharide; Receptor; Flow cytometry; Chemistry; Biology; Molecular biology; Biochemistry; Endocrinology; Immunology; Cholesterol; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001554056,0.000313906,0.0003697218,0.0002176428,0.0002307506,0.0003207398,0.0001490215,0.0002248548,0.002411479],"category_scores_gemma":[0.0001221713,0.0001407104,0.000438603,0.000238572,0.0001845164,0.0001614516,0.0002034516,0.0006081939,0.001386199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000339069,"about_ca_system_score_gemma":0.0002441241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001707182,"about_ca_topic_score_gemma":0.001485276,"domain_scores_codex":[0.9997055,0.00005159378,0.00004246584,0.00004448562,0.00007649525,0.00007952101],"domain_scores_gemma":[0.9999075,0.00001585773,0.00001805266,0.00001533497,0.00002050252,0.00002277583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005658371,0.0000927912,0.0005326613,0.00007419212,0.000009645074,0.0000832359,0.00002454917,0.00005972363,0.9970552,0.00004984797,0.000248955,0.001203269],"study_design_scores_gemma":[0.00007248958,0.0003067504,0.007530231,0.00000783172,0.00001924567,0.0002306836,0.00005789617,0.001398432,0.9879497,0.00002854377,0.002390342,0.000007874649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883903,0.00254428,0.003040597,0.0003475628,0.0001407827,0.00006899128,0.001687662,0.000256839,0.003523001],"genre_scores_gemma":[0.9861349,0.001169811,0.002277519,0.0001403635,0.00002846,0.0001304602,0.002145156,0.00003815866,0.007935133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002411479,"threshold_uncertainty_score":0.008067191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01548834752103454,"score_gpt":0.2612835228842583,"score_spread":0.2457951753632238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}