{"id":"W4313382844","doi":"10.4049/jimmunol.202.supp.190.21","title":"Long Pentraxin 3 (PTX3) Regulates IL-17A Mediated Immunity to Primary and Secondary <i>Leishmania major</i> Infection","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Biomarkers in Disease Mechanisms","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"PTX3; Leishmania major; Inflammation; Immunology; Pathogenesis; Biology; Immune system; Effector; Acquired immune system; Interleukin 17; Innate immune system; Cutaneous leishmaniasis; Immunity; Leishmania; Leishmaniasis; Parasite hosting","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009574394,0.0002987261,0.000196956,0.0001558444,0.0001369482,0.0003293115,0.0001264898,0.0002970191,0.00152893],"category_scores_gemma":[0.00008449581,0.0001410709,0.0003537686,0.00008129009,0.0002944298,0.0001409368,0.0002126814,0.0008158311,0.0005400193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002649753,"about_ca_system_score_gemma":0.0001388199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002989136,"about_ca_topic_score_gemma":0.0003771269,"domain_scores_codex":[0.9998755,0.00002132731,0.00001242503,0.0000225508,0.00002151632,0.00004656571],"domain_scores_gemma":[0.9998617,0.0000119064,0.00006225795,0.00001004662,0.0000116317,0.00004245672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002301787,0.00002006946,0.0003535133,0.00002487464,0.000002689932,0.00005798947,0.000007972096,0.00002487599,0.9988286,0.00002425098,0.00003845615,0.0003865266],"study_design_scores_gemma":[0.0001035289,0.00103122,0.04804545,0.00002872476,0.0000495451,0.001197277,0.0001668638,0.001339457,0.9450987,0.0001370104,0.002791346,0.00001081427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970787,0.0006136437,0.0008159809,0.0001220748,0.00002281094,0.0000253551,0.0003806209,0.00007265191,0.0008682651],"genre_scores_gemma":[0.9969227,0.0003768486,0.0006025115,0.0001211859,0.00001342758,0.00003347192,0.0004912516,0.00002846664,0.001410149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00152893,"threshold_uncertainty_score":0.005114734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004697186689867419,"score_gpt":0.1993456167319913,"score_spread":0.1946484300421238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}