{"id":"W4313385181","doi":"10.4049/jimmunol.198.supp.67.25","title":"IDO1 activity in selected immune cells controls antibody responses","year":2017,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Antibody; Immune system; Immune tolerance; Ovalbumin; Immunology; Indoleamine 2,3-dioxygenase; Kynurenine; CD11c; Immunization; Antigen; Biology; Chemistry; Gene; Tryptophan; Biochemistry; Phenotype; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001476687,0.0003148207,0.0004760482,0.0003000122,0.0001837387,0.0004215156,0.0001914196,0.0003063462,0.001972435],"category_scores_gemma":[0.0001436401,0.0001224237,0.0001614654,0.000206862,0.000253236,0.000151494,0.0002187231,0.0007566989,0.00075146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003569915,"about_ca_system_score_gemma":0.0001403133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002153548,"about_ca_topic_score_gemma":0.0003466848,"domain_scores_codex":[0.9996911,0.00003412669,0.00002386686,0.0000984562,0.00004924555,0.0001032759],"domain_scores_gemma":[0.9998186,0.00002917445,0.00003816907,0.00002736982,0.0000185857,0.00006817253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002582827,0.00003664961,0.0003442209,0.00002872807,0.000001579439,0.0000207923,0.000008055229,0.00001889715,0.9986676,0.00003257005,0.00002942751,0.0005532301],"study_design_scores_gemma":[0.00003435456,0.0004720231,0.009324441,0.000007946685,0.00002431345,0.0001455973,0.00003345089,0.0005700383,0.9867715,0.00005207934,0.002559815,0.000004396763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928855,0.002001502,0.001903475,0.0000594657,0.00008588233,0.00004892382,0.001030072,0.0001045856,0.00188058],"genre_scores_gemma":[0.9931698,0.000580064,0.001520484,0.000077411,0.00004830518,0.0001081484,0.001338312,0.0000412296,0.003116245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001972435,"threshold_uncertainty_score":0.006598473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01264126112145842,"score_gpt":0.2759195810627176,"score_spread":0.2632783199412592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}