{"id":"W4313386340","doi":"10.4049/jimmunol.190.supp.51.6","title":"Tregs from T1D subjects with a susceptible IL-2R gene SNP, respond aberrantly to IL-2 stimulation. (P4080)","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia Hospital","funders":"","keywords":"STAT5; Biology; Effector; Single-nucleotide polymorphism; Genotype; Receptor; STAT protein; Gene; Interleukin 2; Locus (genetics); Immunology; Cytokine; Genetics; STAT3","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001480628,0.0002691608,0.0003225776,0.0004293239,0.0003390764,0.0002018758,0.00009068843,0.0002666075,0.004349259],"category_scores_gemma":[0.0002641691,0.0001080231,0.0001798209,0.0001697422,0.000151912,0.00008857372,0.0001621656,0.0004221663,0.0005697124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006738257,"about_ca_system_score_gemma":0.00007309609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004325841,"about_ca_topic_score_gemma":0.000591458,"domain_scores_codex":[0.99986,0.00002361809,0.00001724636,0.00003465977,0.00003434502,0.00002999765],"domain_scores_gemma":[0.9998318,0.00003712648,0.00002282827,0.00001496879,0.00001938118,0.00007381723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.007627239,0.0008716476,0.06977601,0.0001397503,0.00008208273,0.001426828,0.0003410608,0.0001157027,0.9096066,0.00008390738,0.0009606575,0.008968471],"study_design_scores_gemma":[0.0008666621,0.006675408,0.8685534,0.00004680897,0.0002563791,0.007902451,0.0009546475,0.001015643,0.1085902,0.0004143069,0.004686579,0.00003743557],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987271,0.0001386919,0.0001717382,0.0000262124,0.00002504174,0.00002044742,0.0004202585,0.00000930658,0.0004612677],"genre_scores_gemma":[0.9977168,0.00006465918,0.0002145133,0.0000996412,0.00004000631,0.00004650808,0.0007546373,0.000006707438,0.001056691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004349259,"threshold_uncertainty_score":0.01454973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007182090063244658,"score_gpt":0.2194461393935701,"score_spread":0.2122640493303254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}