{"id":"W4313389229","doi":"10.3390/cancers15010276","title":"Tumor Microenvironment before and after Chemoradiation in Locally Advanced Rectal Cancer: Beyond PD-L1","year":2022,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Northeast Cancer Centre","funders":"","keywords":"Colorectal cancer; Tumor microenvironment; Medicine; Cancer research; Cancer; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002368883,0.00009251927,0.0002450555,0.0003654489,0.0001832231,0.000543679,0.0001142342,0.00020137,0.001181038],"category_scores_gemma":[0.0004254397,0.00008832625,0.0001620508,0.0003583638,0.00022562,0.0003198967,0.0001921848,0.0002899368,0.0002217612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004859989,"about_ca_system_score_gemma":0.0003001049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000959023,"about_ca_topic_score_gemma":0.001823612,"domain_scores_codex":[0.999874,0.000034726,0.000009001576,0.00002537308,0.00002551813,0.00003135537],"domain_scores_gemma":[0.9997004,0.00005605425,0.0001388579,0.00001595935,0.00003670648,0.00005201821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00479788,0.0001732731,0.8055953,0.0003789867,0.00007845896,0.001778974,0.0005252972,0.0004604324,0.1376598,0.00009951397,0.0006310042,0.04782097],"study_design_scores_gemma":[0.00001428227,0.0009217064,0.9780225,0.00003270367,0.00005453095,0.001843589,0.0005631581,0.0003899953,0.01559743,0.00007914172,0.002469721,0.00001133235],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953134,0.003293062,0.0002364643,0.0001270042,0.00001409787,0.0000194817,0.0002000955,0.00001517468,0.0007811751],"genre_scores_gemma":[0.9987894,0.0005089622,0.0002188637,0.00004589623,0.00001202641,0.00001149952,0.0001519301,0.00000266246,0.0002589067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001181038,"threshold_uncertainty_score":0.003950953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003951185176001459,"score_gpt":0.2237904483871253,"score_spread":0.2198392632111238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}