{"id":"W4313401455","doi":"10.1007/978-1-0716-2875-1_21","title":"Generating Human Pluripotent Stem Cell-Derived Neural AssemBloids™ to Model Interneuron Migration and Immune Cell Interactions","year":2023,"lang":"en","type":"book-chapter","venue":"Neuromethods","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Stemcell Technologies","funders":"","keywords":"Organoid; Induced pluripotent stem cell; Neuroscience; Interneuron; Biology; Neural stem cell; Microglia; Embryonic stem cell; Stem cell; Cell biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002422776,0.0003501037,0.0001579824,0.0002324728,0.0001431547,0.0004324894,0.0004255687,0.0003653259,0.003604817],"category_scores_gemma":[0.0000736232,0.0001919063,0.0002759881,0.0001907268,0.0002458223,0.0004387918,0.0003309264,0.0006216813,0.001517254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000293672,"about_ca_system_score_gemma":0.000155135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003103716,"about_ca_topic_score_gemma":0.0006927252,"domain_scores_codex":[0.9999399,0.000005001468,0.000004363123,0.0000121823,0.0000334379,0.000004938826],"domain_scores_gemma":[0.9999729,0.000009853501,0.000004111846,0.00000376361,0.000005735445,0.000003611464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003637161,0.00004066619,0.000145953,0.0002966726,0.00001485375,0.0001947869,0.00007015347,0.001862798,0.9031178,0.03090793,0.002760354,0.06055161],"study_design_scores_gemma":[0.00001801415,0.0001309137,0.0006968711,0.00006781208,0.00003105107,0.000561178,0.00003379436,0.004213101,0.8294641,0.009300037,0.1554667,0.00001645396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1677821,0.03817955,0.5837494,0.00149519,0.00205838,0.0006480254,0.004278879,0.00124734,0.2005612],"genre_scores_gemma":[0.3699279,0.04103558,0.3370342,0.001077853,0.0001619422,0.000720311,0.005061411,0.0003825397,0.2445983],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003604817,"threshold_uncertainty_score":0.01205933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05451783867617999,"score_gpt":0.3258513700061595,"score_spread":0.2713335313299796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}