{"id":"W4313404855","doi":"10.4049/jimmunol.208.supp.54.19","title":"Chimeric antigen receptors on Regulatory T cells as a treatment strategy in autoimmune diseases","year":2022,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chimeric antigen receptor; Immunology; Flow cytometry; CD28; Regulatory T cell; T cell; FOXP3; Biology; Cancer research; IL-2 receptor; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002918747,0.0002203005,0.0003210843,0.0001484055,0.0000580952,0.0002655397,0.0002193086,0.0004561743,0.001420157],"category_scores_gemma":[0.0001256351,0.00006089765,0.0001982867,0.00008776005,0.000191222,0.0001997446,0.0001164173,0.0006731629,0.0003908217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001394841,"about_ca_system_score_gemma":0.0001541114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001227428,"about_ca_topic_score_gemma":0.0001582525,"domain_scores_codex":[0.999908,0.00002823052,0.000004400551,0.00001250596,0.00002375274,0.00002315817],"domain_scores_gemma":[0.9999522,0.00001422948,0.00001125563,0.000004864255,0.000007341206,0.00001009006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.002556793,0.001043876,0.0009312648,0.0006979755,0.00009587818,0.0006337593,0.00008445676,0.002036256,0.7895207,0.005425136,0.002758247,0.1942157],"study_design_scores_gemma":[0.004044599,0.04270616,0.006387138,0.000395974,0.0007795112,0.004689591,0.0001686512,0.009922478,0.7901044,0.003368788,0.1373769,0.00005585616],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9111306,0.06017265,0.01514433,0.002318954,0.0006253771,0.0002603939,0.0002083292,0.0005755367,0.009563739],"genre_scores_gemma":[0.9781578,0.01198247,0.004235582,0.0005614398,0.0001572963,0.0001244927,0.000138914,0.00002251756,0.004619576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001420157,"threshold_uncertainty_score":0.004750967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01058021524851001,"score_gpt":0.2256260399327989,"score_spread":0.2150458246842888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}