{"id":"W4313405693","doi":"10.4049/jimmunol.208.supp.105.34","title":"The CD6-ALCAM pathway selectively modulates pathogenic T cell migration","year":2022,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trillium Therapeutics (Canada)","funders":"","keywords":"ALCAM; Cell biology; Chemokine; Chemistry; Chemotaxis; CCL21; Cell migration; Inflammation; Chemokine receptor; Biology; Immunology; Receptor; In vitro; Cell adhesion molecule; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009354872,0.0002887141,0.0002322063,0.0001312153,0.0001549513,0.0002935228,0.0001358052,0.000269199,0.001765365],"category_scores_gemma":[0.00007342465,0.00009430853,0.0001930669,0.00009265648,0.0001165801,0.0001540888,0.0001203562,0.0006432615,0.0003939654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001741193,"about_ca_system_score_gemma":0.0001204927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002771438,"about_ca_topic_score_gemma":0.0004076557,"domain_scores_codex":[0.999797,0.00004921532,0.00001526064,0.00002811383,0.00003366165,0.00007677253],"domain_scores_gemma":[0.9999475,0.00001013718,0.00001048037,0.000005277869,0.000008378302,0.00001817472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001095001,0.00003957068,0.00008327244,0.0000287016,0.000002470054,0.00001230897,0.000006139213,0.00001831906,0.9989931,0.00003020406,0.00003087189,0.0006455395],"study_design_scores_gemma":[0.00002509695,0.0005354939,0.003573397,0.000007892821,0.00001596151,0.0001464441,0.000027841,0.0008736932,0.9927268,0.00003256557,0.002032133,0.000002746713],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949849,0.001986852,0.001354714,0.00008390604,0.00003981877,0.00002567083,0.000172458,0.00005488312,0.001296943],"genre_scores_gemma":[0.995859,0.0008015312,0.001516417,0.00006630832,0.00001857317,0.00004215364,0.0002548426,0.00001043294,0.001430858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001765365,"threshold_uncertainty_score":0.005905747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007082264595395868,"score_gpt":0.1979125901867583,"score_spread":0.1908303255913625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}