{"id":"W4313405780","doi":"10.4049/jimmunol.208.supp.108.14","title":"Sex-Dependent Differences in Serum Autoantibody Levels in the 3×Tg-AD Model of Alzheimer’s Disease","year":2022,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Autoantibody; Internal medicine; Endocrinology; Antibody; Antigen; Anti-nuclear antibody; Disease; Orchiectomy; Medicine; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002142813,0.0004385177,0.000379819,0.0009566562,0.0001712221,0.0003206888,0.0001409817,0.0003180102,0.001631619],"category_scores_gemma":[0.0001271414,0.000195052,0.0003489704,0.0002672784,0.0002643802,0.0002241747,0.0001660855,0.0007852584,0.0003313409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002368124,"about_ca_system_score_gemma":0.0001246536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005201743,"about_ca_topic_score_gemma":0.0009561906,"domain_scores_codex":[0.9997836,0.00002043716,0.00002515895,0.00005713907,0.00006705408,0.00004659145],"domain_scores_gemma":[0.9997066,0.00002293444,0.0001278056,0.0000244429,0.00003786823,0.00008041719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007767989,0.0001620211,0.002409705,0.00002849228,0.00001407744,0.0001252949,0.00003460479,0.00001264504,0.9951276,0.00003398762,0.00005605904,0.001218816],"study_design_scores_gemma":[0.0001190972,0.004292581,0.2834411,0.00003144998,0.0001426299,0.00207905,0.0002546397,0.0005019751,0.705731,0.0002040754,0.003161167,0.00004119767],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966298,0.001103593,0.0006065285,0.00005260932,0.00004147848,0.00002394746,0.0006645689,0.0000553681,0.0008221744],"genre_scores_gemma":[0.9930494,0.0008858614,0.0009596352,0.00009998828,0.0000235246,0.00007977852,0.001025955,0.00003527068,0.003840559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001631619,"threshold_uncertainty_score":0.005458295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0396465778778422,"score_gpt":0.2575112220734204,"score_spread":0.2178646441955782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}