{"id":"W4313406001","doi":"10.4049/jimmunol.208.supp.110.20","title":"Modulating levels of cell surface CD6 is a novel mechanism for regulating T cell activity.","year":2022,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trillium Therapeutics (Canada)","funders":"","keywords":"T cell; IL-2 receptor; Cell biology; Chemistry; Cytotoxic T cell; Cell; Cytokine; Cell growth; Receptor; Immune system; Biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232122,0.0003275768,0.0001822976,0.0001580099,0.0001337842,0.0004339766,0.0002578886,0.0003220755,0.002111307],"category_scores_gemma":[0.0001123297,0.00009619776,0.0002440684,0.0001117651,0.0002046768,0.0002684362,0.0001804449,0.0006826919,0.0006316641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002171345,"about_ca_system_score_gemma":0.0001082702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009734721,"about_ca_topic_score_gemma":0.0001442812,"domain_scores_codex":[0.9998636,0.00002286497,0.000009736563,0.00003293906,0.0000425519,0.00002820338],"domain_scores_gemma":[0.9999138,0.000009500741,0.00002871995,0.00001116846,0.00001404397,0.00002275793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009908204,0.00001857277,0.0001461507,0.00003481907,0.000003539794,0.00002980818,0.000004500817,0.00003019674,0.9957625,0.0001615944,0.000065608,0.003643593],"study_design_scores_gemma":[0.00004103948,0.0006284873,0.004238589,0.00001285673,0.00002365659,0.0005912947,0.00001358831,0.001095852,0.9843304,0.0002448793,0.008774507,0.00000489293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9359884,0.02283863,0.03042693,0.0006705401,0.0003926835,0.00009646043,0.0005401425,0.0003637025,0.008682554],"genre_scores_gemma":[0.9855739,0.002711348,0.007374194,0.0001408184,0.00007612685,0.00003452438,0.0002698694,0.00001945671,0.003799784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002111307,"threshold_uncertainty_score":0.007063031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0355806426679016,"score_gpt":0.2775114220200117,"score_spread":0.24193077935211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}