{"id":"W4313407982","doi":"10.4049/jimmunol.208.supp.170.37","title":"Hypoxia promotes cytolytic activity of CD8 T cells and pathogenesis in cutaneous leishmaniasis","year":2022,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Cytotoxic T cell; CD8; Immunology; Biology; Leishmania major; Cutaneous leishmaniasis; In vitro; Leishmaniasis; Immune system; Leishmania; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007139974,0.0001474187,0.0001166741,0.0001073642,0.00007593445,0.000112978,0.00006068427,0.0001736668,0.001463532],"category_scores_gemma":[0.00006392629,0.00008258752,0.00008954919,0.00005423871,0.00009218023,0.00009793547,0.0001024685,0.0003638932,0.0002682395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009847138,"about_ca_system_score_gemma":0.00003812557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000128729,"about_ca_topic_score_gemma":0.000121948,"domain_scores_codex":[0.9999424,0.00001666148,0.000004253409,0.00001071527,0.000008317794,0.00001761488],"domain_scores_gemma":[0.999957,0.000006358431,0.0000108042,0.000003883277,0.000005679708,0.00001618932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003503046,0.00004790016,0.0007573394,0.00004122657,0.000002533333,0.00007447497,0.00001176329,0.00002790024,0.9971434,0.00002530954,0.00005421937,0.001463599],"study_design_scores_gemma":[0.0001961013,0.002769529,0.1090081,0.00003240506,0.00004208124,0.001343482,0.0001869768,0.002882767,0.8772025,0.0002534495,0.006075682,0.000006971535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967794,0.001545218,0.0005936573,0.00006889051,0.00002419768,0.00002143305,0.00007216572,0.00002546313,0.0008695588],"genre_scores_gemma":[0.9986539,0.0003036078,0.0002138359,0.00003817703,0.00001569233,0.00001891579,0.00006880968,0.00000211313,0.0006849097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001463532,"threshold_uncertainty_score":0.004895985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0220152170558872,"score_gpt":0.2705861707039618,"score_spread":0.2485709536480746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}