{"id":"W4313410397","doi":"10.1016/j.ydbio.2022.12.007","title":"Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier","year":2022,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Ocean Acidification Effects and Responses","field":"Earth and Planetary Sciences","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Sleep Foundation","keywords":"Biology; Strongylocentrotus purpuratus; Septate junctions; Cell biology; Paracellular transport; Morpholino; Tight junction; Sea urchin; Hindgut; Gene; Transcriptome; Claudin; Bilateria; Gene knockdown; Genetics; Gene expression; Cell junction; Cell; Midgut; Botany; Phylogenetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004335119,0.0001333263,0.0001118068,0.0003206239,0.0002153221,0.0002256731,0.00008797505,0.0001960645,0.0008794754],"category_scores_gemma":[0.0001557361,0.0001415027,0.00009838082,0.0001632272,0.0002032209,0.0001478001,0.000219207,0.0002016359,0.0001962567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001704664,"about_ca_system_score_gemma":0.0001632152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001749527,"about_ca_topic_score_gemma":0.004322348,"domain_scores_codex":[0.9999617,0.000003532835,0.000002480677,0.00001171046,0.000008138842,0.00001244585],"domain_scores_gemma":[0.999836,0.00003114254,0.00005446308,0.00001086278,0.00002550531,0.00004203903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001184187,0.000006282904,0.00734678,0.00001613386,0.000003690606,0.00009686675,0.00005345911,0.00003124457,0.9907203,0.0001162848,0.00003650329,0.001454101],"study_design_scores_gemma":[0.00001708726,0.0002206717,0.8301116,0.00001162467,0.00002633191,0.0007980984,0.000414496,0.001087653,0.1646644,0.0001406189,0.002497455,0.00000980508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986954,0.0001984422,0.0003507554,0.00002959788,0.000002756615,0.000003331353,0.0003045751,0.000006736029,0.0004085057],"genre_scores_gemma":[0.9963167,0.0001258048,0.0008199592,0.00003051354,0.000003271619,0.00001132893,0.0007666607,0.000005265394,0.001920399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001749527,"threshold_uncertainty_score":0.003478646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01595475521578194,"score_gpt":0.2216711361805007,"score_spread":0.2057163809647187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}