{"id":"W4313410397","doi":"10.1016/j.ydbio.2022.12.007","title":"Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier","year":2022,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Ocean Acidification Effects and Responses","field":"Earth and Planetary Sciences","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Sleep Foundation","keywords":"Biology; Strongylocentrotus purpuratus; Septate junctions; Cell biology; Paracellular transport; Morpholino; Tight junction; Sea urchin; Hindgut; Gene; Transcriptome; Claudin; Bilateria; Gene knockdown; Genetics; Gene expression; Cell junction; Cell; Midgut; Botany; Phylogenetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007239432,0.00007486845,0.0001171251,0.00005560724,0.0003414853,0.000008603023,0.0003524666,0.0000253333,0.00001666549],"category_scores_gemma":[0.00007203045,0.00003615524,0.00004234967,0.0002121909,0.0001416848,0.00009542915,0.00007813852,0.00007039108,2.371063e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001796748,"about_ca_system_score_gemma":0.0001043872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002001755,"about_ca_topic_score_gemma":0.0002109009,"domain_scores_codex":[0.9987133,0.0004315822,0.0004286674,0.0001211801,0.000188928,0.0001164078],"domain_scores_gemma":[0.9991911,0.0001772993,0.0004461376,0.0001344503,0.000038771,0.00001224232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001682586,0.00001443889,0.4102527,0.00007032821,0.00001563003,3.156568e-8,0.004597334,0.0003717086,0.5816003,0.00001823688,0.000004162247,0.002886826],"study_design_scores_gemma":[0.0001873093,0.00002009887,0.7312239,0.00003665844,0.000007076047,0.000003334085,0.001247799,0.0009352007,0.2661944,0.00003196154,0.00007703873,0.00003523711],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985285,0.0003586142,0.00005597709,0.0001208463,0.0001746926,0.0006523034,0.00009755872,0.000002106514,0.000009411966],"genre_scores_gemma":[0.9997786,0.00002820871,0.0001073592,0.00001657292,0.000004443938,0.0000186011,0.00002501887,0.000001748164,0.00001948714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3209711,"threshold_uncertainty_score":0.2626463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01595475521578194,"score_gpt":0.2216711361805007,"score_spread":0.2057163809647187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}