{"id":"W4313414521","doi":"10.3390/biomedicines11010068","title":"Indisulam Reduces Viability and Regulates Apoptotic Gene Expression in Pediatric High-Grade Glioma Cells","year":2022,"lang":"en","type":"article","venue":"Biomedicines","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Apoptosis; Glioma; Viability assay; Gene; Cancer research; Gene expression; Biology; Cell biology; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005630065,0.000192266,0.0002334092,0.0001910706,0.00009683198,0.000175661,0.0001609034,0.0001609609,0.0007339966],"category_scores_gemma":[0.00007829269,0.00006356721,0.0001351409,0.0002188852,0.0001204847,0.0001172002,0.0000827421,0.0003191141,0.000168105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001890992,"about_ca_system_score_gemma":0.0001879938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008972761,"about_ca_topic_score_gemma":0.001371803,"domain_scores_codex":[0.9999406,0.00001134084,0.000005761964,0.00000910164,0.00001741385,0.00001576154],"domain_scores_gemma":[0.9999535,0.000009254633,0.00001286744,0.000005580201,0.000009342138,0.000009445575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005474573,0.0001023634,0.0008478133,0.0001238255,0.00001197926,0.00009687814,0.00004283476,0.00007731102,0.9928581,0.00004775606,0.0001396131,0.005104141],"study_design_scores_gemma":[0.00003449307,0.0012157,0.01501106,0.000008838705,0.00003335295,0.0003898058,0.0001132496,0.0005848874,0.979456,0.00003082953,0.003117863,0.00000393682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932547,0.004785631,0.0005339249,0.00007149738,0.00001799082,0.00001148815,0.0002400081,0.00005097616,0.001033828],"genre_scores_gemma":[0.9952513,0.002340766,0.0006989739,0.00004220779,0.000008433864,0.00002294579,0.0005595758,0.000007829876,0.001067891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008972761,"threshold_uncertainty_score":0.002455473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01184689909703121,"score_gpt":0.2488396319964482,"score_spread":0.236992732899417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}