{"id":"W4313423569","doi":"10.4049/jimmunol.208.supp.57.02","title":"Epigenome accessibility changes before and after activation reveal distinct and progressive differentiation for human memory T cell subsets","year":2022,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Epigenetics; Biology; Chromatin; Epigenome; CD8; T cell; Cell biology; Gene; Gene expression; Genetics; Immune system; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008140428,0.00009205603,0.000135146,0.0004344603,0.00009512901,0.0002280342,0.00007834519,0.0001559873,0.001827272],"category_scores_gemma":[0.0001595844,0.00009529425,0.0001083967,0.000279497,0.00009836749,0.0001150548,0.0001304312,0.000170154,0.0002872465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007338804,"about_ca_system_score_gemma":0.00004495945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000373982,"about_ca_topic_score_gemma":0.0004602512,"domain_scores_codex":[0.9999365,0.000007900734,0.000004136553,0.00002341198,0.000009475231,0.00001863102],"domain_scores_gemma":[0.9999145,0.00001922098,0.00002419004,0.000009924277,0.00001634933,0.00001577051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005141031,0.00002060034,0.03159709,0.00003247673,0.00002484119,0.00007344223,0.0001201637,0.0000542025,0.9608372,0.00005806009,0.00006124705,0.006606483],"study_design_scores_gemma":[0.00001001312,0.0003471602,0.8085616,0.000007745776,0.00005504148,0.000800464,0.0002909338,0.0006981228,0.1876247,0.0001548934,0.001439525,0.000009811657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976183,0.0006292645,0.0008140175,0.00001287855,0.00000343127,0.000005043448,0.0004338382,0.0000184891,0.0004647397],"genre_scores_gemma":[0.9985568,0.0001657043,0.0002859946,0.00001287163,0.000004407271,0.00001092636,0.0004438945,0.000004251799,0.0005150151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001827272,"threshold_uncertainty_score":0.006112814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01162390295979286,"score_gpt":0.2485448030147661,"score_spread":0.2369209000549733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}