{"id":"W4313423974","doi":"10.1093/infdis/jiac501","title":"Unique Profile of Inflammation and Immune Activation in Pregnant People With HIV in the United States","year":2023,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institute on Alcohol Abuse and Alcoholism; University of California, San Diego; NIH Office of the Director; SUNY Downstate Medical Center; National Institute of Child Health and Human Development; Tulane University; University of Illinois at Urbana-Champaign; Harvard T.H. Chan School of Public Health; National Institute on Deafness and Other Communication Disorders; National Institute on Drug Abuse; York University; University of Miami; National Institute of Neurological Disorders and Stroke; School of Medicine, New York University; National Institute of Dental and Craniofacial Research; Thrasher Research Fund; State University of New York; University of Southern California; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Pregnancy; Medicine; Inflammation; Immune system; Confounding; Cohort; Human immunodeficiency virus (HIV); Biomarker; Immunology; Antiretroviral therapy; Gestation; C-reactive protein; Internal medicine; Viral load; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000310649,0.0001185155,0.0001942865,0.0004018649,0.0003196668,0.0002919265,0.000122347,0.0002190029,0.0005785021],"category_scores_gemma":[0.0008679641,0.0001185049,0.0001310892,0.0006203821,0.0001704632,0.0001666717,0.0002588491,0.0002628694,0.00006106339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001908579,"about_ca_system_score_gemma":0.0003315589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005673313,"about_ca_topic_score_gemma":0.01053935,"domain_scores_codex":[0.9998333,0.00005886467,0.00002294081,0.00003108747,0.00002996637,0.00002390108],"domain_scores_gemma":[0.9996159,0.00006608846,0.0001922988,0.00001857862,0.00004417021,0.00006281499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00002594771,0.000008090871,0.9979663,0.000007723647,0.0000128325,0.00005373467,0.00009236775,0.00001076371,0.0001468047,0.00001099332,0.00007854227,0.001586005],"study_design_scores_gemma":[0.000001649799,0.00003700245,0.999055,0.00001424085,0.00001344805,0.0003062199,0.0002661444,0.00005100016,0.00003985853,0.00003117245,0.0001826966,0.000001597598],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978928,0.000840618,0.00006723792,0.0001355187,0.000008870646,0.000008147424,0.0005206806,0.000003058899,0.0005230388],"genre_scores_gemma":[0.9991047,0.0004250081,0.0001155882,0.00007146606,0.000008924159,0.000009060823,0.0002106912,5.872905e-7,0.00005409992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005673313,"threshold_uncertainty_score":0.0112806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009633595091975016,"score_gpt":0.2750334639352465,"score_spread":0.2653998688432714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}