{"id":"W4313430239","doi":"10.4049/jimmunol.208.supp.165.04","title":"Choline metabolism underpins macrophage IL-4 polarization <i>in vitro</i> and <i>in vivo</i>","year":2022,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Choline; Macrophage polarization; Macrophage; In vivo; Phosphatidylcholine; Metabolism; Biology; Inflammation; Biochemistry; Cell biology; Chemistry; In vitro; Immunology; Phospholipid; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001627799,0.000473508,0.0003490261,0.0003009306,0.0001821338,0.0003757044,0.0001820327,0.0003890008,0.001711524],"category_scores_gemma":[0.00008357219,0.0002173487,0.0003605596,0.000181188,0.0003618915,0.0002498168,0.000221971,0.001048125,0.0006177141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003680908,"about_ca_system_score_gemma":0.000227253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009084404,"about_ca_topic_score_gemma":0.001110024,"domain_scores_codex":[0.9997974,0.00004242801,0.00001678664,0.00003873281,0.00003709891,0.00006759368],"domain_scores_gemma":[0.9998895,0.000007856522,0.00004433505,0.00001028844,0.00001825555,0.00002972526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003323225,0.00002088096,0.0001319111,0.00003188776,0.000003819209,0.00001533954,0.000005123828,0.00002191938,0.9990778,0.00002326515,0.00003428989,0.000301433],"study_design_scores_gemma":[0.00002030228,0.0003431259,0.003699163,0.000007074378,0.00002034602,0.00008768389,0.00003657572,0.00028109,0.9946743,0.0000312619,0.0007950858,0.000003876557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900241,0.002771307,0.003349748,0.0003834323,0.000066463,0.00004023012,0.001326595,0.0001970709,0.001841148],"genre_scores_gemma":[0.994218,0.001045758,0.001472947,0.0001509477,0.00001816468,0.00005648666,0.0008024091,0.00004041457,0.002194902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001711524,"threshold_uncertainty_score":0.005725622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008449120293391605,"score_gpt":0.2162593358231464,"score_spread":0.2078102155297548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}