{"id":"W4313431583","doi":"10.1080/10428194.2022.2148221","title":"Corticosteroid tapering is a safe approach in patients with relapsed or refractory multiple myeloma receiving subcutaneous daratumumab: part 3 of the open-label, multicenter, phase 1b PAVO study","year":2023,"lang":"en","type":"article","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Janssen Research and Development","keywords":"Daratumumab; Medicine; Tapering; Refractory (planetary science); Open label; Multicenter study; Multiple myeloma; Phases of clinical research; Oncology; Internal medicine; Clinical trial; Computer science; Materials science; Lenalidomide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010882,0.0001933665,0.0008084938,0.0001947896,0.0002272112,0.0005750774,0.0001995072,0.000361759,0.001975316],"category_scores_gemma":[0.001451651,0.0001425285,0.0008571355,0.0003389838,0.0002019335,0.0002988896,0.0001684938,0.0009938197,0.0002875759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003791154,"about_ca_system_score_gemma":0.0009055561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005631971,"about_ca_topic_score_gemma":0.002616346,"domain_scores_codex":[0.9996194,0.0001270834,0.0000389549,0.00004472752,0.0001258094,0.00004403329],"domain_scores_gemma":[0.9992571,0.0002392639,0.0002704251,0.00004017054,0.00005812355,0.0001348385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.234224,0.00548529,0.07233564,0.001936558,0.002578945,0.0007610002,0.0002694966,0.0007478606,0.01768022,0.0004464933,0.01158939,0.6519451],"study_design_scores_gemma":[0.2085671,0.1928971,0.5306998,0.001163481,0.004771483,0.003529866,0.0004644592,0.004126245,0.009418304,0.001476698,0.04276116,0.0001242822],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.950043,0.03873869,0.0009370159,0.002037439,0.0004249823,0.000731701,0.0009384119,0.00008865885,0.00606027],"genre_scores_gemma":[0.9901877,0.006227772,0.0008743196,0.0009213614,0.0002891014,0.0002065815,0.0006209378,0.000008409748,0.0006639002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001975316,"threshold_uncertainty_score":0.006608129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03396421959788129,"score_gpt":0.2982158978671249,"score_spread":0.2642516782692436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}