{"id":"W4313431752","doi":"10.4049/jimmunol.208.supp.60.04","title":"A dietary fiber limits autoimmune neuroinflammation by restricting Th1 activation, polarization, and migration","year":2022,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Experimental autoimmune encephalomyelitis; Immune system; Guar gum; Neuroinflammation; T cell; Immunology; Multiple sclerosis; Inflammation; Adoptive cell transfer; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001001952,0.000331958,0.0002335492,0.0003090043,0.000128291,0.0003272051,0.0001249552,0.0002301321,0.001220476],"category_scores_gemma":[0.00008140661,0.0001056571,0.0001677423,0.0001418085,0.000189458,0.0002227035,0.0001619735,0.0003733362,0.0001787793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001416901,"about_ca_system_score_gemma":0.0001431314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000400867,"about_ca_topic_score_gemma":0.000741578,"domain_scores_codex":[0.9999033,0.00001330462,0.000009550005,0.00002835789,0.00002543173,0.00002002703],"domain_scores_gemma":[0.9999019,0.000009151437,0.00003745629,0.000007799769,0.00001560273,0.00002811187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003183662,0.0000496796,0.0002213938,0.00004970723,0.000006345177,0.000008774266,0.000005558338,0.00001748948,0.9981543,0.00001665281,0.00001506263,0.001136594],"study_design_scores_gemma":[0.00005962986,0.003181006,0.02800824,0.00006414125,0.0000984439,0.0001427971,0.00008724874,0.0006644868,0.9633245,0.0001052661,0.00425344,0.0000107979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975,0.0009848332,0.0006501771,0.00004724414,0.00001888516,0.0000148917,0.0002307449,0.00002729672,0.0005259193],"genre_scores_gemma":[0.9937106,0.001030187,0.002690183,0.00006719813,0.00001729861,0.00003516274,0.0004240413,0.00001856261,0.002006827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001220476,"threshold_uncertainty_score":0.004082859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02276349586564595,"score_gpt":0.2348307578572928,"score_spread":0.2120672619916469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}