{"id":"W4313439076","doi":"10.1038/s41581-022-00662-0","title":"Gasdermins and pyroptosis in the kidney","year":2023,"lang":"en","type":"review","venue":"Nature Reviews Nephrology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":177,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Pyroptosis; Inflammasome; Programmed cell death; Cell biology; Secretion; Caspase 1; Effector; Medicine; Apoptosis; Biology; Immunology; Inflammation; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000865687,0.001040308,0.001759069,0.001544598,0.0002521278,0.001369136,0.0009730309,0.001664666,0.002939638],"category_scores_gemma":[0.0009138671,0.0002909343,0.0004057192,0.00182112,0.0006726364,0.001589605,0.001024782,0.002574348,0.001815509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007266887,"about_ca_system_score_gemma":0.001424999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008981519,"about_ca_topic_score_gemma":0.001730966,"domain_scores_codex":[0.9997916,0.00003479889,0.00002601725,0.00002858676,0.00009587174,0.00002330274],"domain_scores_gemma":[0.9996397,0.0001345646,0.00005739067,0.00001192174,0.00009215499,0.0000642032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002298316,0.00007161178,0.0001807496,0.01249926,0.0001181901,0.0002946166,0.00004129879,0.0006109755,0.002586408,0.005840741,0.09001139,0.887515],"study_design_scores_gemma":[0.00005731591,0.00007809435,0.0007328436,0.002479182,0.00009793096,0.0009841186,0.00004135687,0.0001112425,0.0003831795,0.004138407,0.9908726,0.00002382493],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004196053,0.9989449,0.00006311909,0.0003283479,0.0003269983,0.000001696362,0.000009614819,0.000004571451,0.0002787801],"genre_scores_gemma":[0.0003299324,0.9984285,0.00008075477,0.0002524291,0.0005369876,0.000003101373,0.00001929051,8.085911e-7,0.000348283],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002939638,"threshold_uncertainty_score":0.009834051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02794038829559604,"score_gpt":0.3460183516519287,"score_spread":0.3180779633563327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}