{"id":"W4313469586","doi":"10.3390/curroncol30010006","title":"Solid Organ Transplantation Is Associated with an Increased Rate of Mismatch Repair Deficiency and PIK3CA Mutations in Colorectal Cancer","year":2022,"lang":"en","type":"article","venue":"Current Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University; National Center for Advancing Translational Sciences; Swim Across America; Johns Hopkins University","keywords":"Medicine; Immunosuppression; Colorectal cancer; Cohort; Internal medicine; Transplantation; Organ transplantation; Oncology; Population; Cancer; Gastroenterology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003468235,0.00009893381,0.0002266337,0.0008502339,0.0002949169,0.0005022898,0.0001689615,0.0002590389,0.002181272],"category_scores_gemma":[0.002188221,0.0001247869,0.0002424063,0.001130411,0.0002199131,0.0002631063,0.0003207307,0.0004016135,0.0001707371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002452275,"about_ca_system_score_gemma":0.0002706744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001845864,"about_ca_topic_score_gemma":0.002248497,"domain_scores_codex":[0.9995419,0.00008170962,0.00007138853,0.00009607091,0.0001349121,0.00007409879],"domain_scores_gemma":[0.9973036,0.0004206634,0.001717817,0.000115077,0.000133392,0.0003094614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007490447,0.00001114677,0.9978387,0.00001064585,0.00001930307,0.0002363007,0.00002069673,0.00001790434,0.0005321293,0.00001106341,0.00005340423,0.001173918],"study_design_scores_gemma":[0.000001494459,0.00002547315,0.9984885,0.000003871191,0.00001326945,0.001097109,0.00006165475,0.00008727636,0.0001256299,0.00001304094,0.00008091736,0.000001700896],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992046,0.0003049054,0.00005727287,0.00003820428,0.000004006266,0.00000281862,0.0001050066,0.000004229422,0.0002789789],"genre_scores_gemma":[0.9997161,0.00008494793,0.0000393333,0.00001317404,0.000007140161,0.000001323119,0.00008735724,0.000001210657,0.00004936414],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002181272,"threshold_uncertainty_score":0.007297039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04237957220364084,"score_gpt":0.3755820197621719,"score_spread":0.3332024475585311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}