{"id":"W4313488947","doi":"10.1002/ejhf.2763","title":"Efficacy of Omecamtiv Mecarbil in Heart Failure with Reduced Ejection Fraction According to N-Terminal Pro-B-Type Natriuretic Peptide Level: Insights from the GALACTIC-HF Trial","year":2023,"lang":"en","type":"article","venue":"European Journal of Heart Failure","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Surgical Specialties (Canada)","funders":"Servier; Cytokinetics; British Heart Foundation; Amgen","keywords":"Medicine; Heart failure; Internal medicine; Ejection fraction; Hazard ratio; Cardiology; Natriuretic peptide; Clinical endpoint; Atrial fibrillation; Population; Placebo; Confidence interval; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001269594,0.0007139185,0.001569452,0.0001814264,0.0001529476,0.0005875936,0.0003951755,0.0006537224,0.001597632],"category_scores_gemma":[0.001685211,0.0001802333,0.001328142,0.0001908068,0.0003837042,0.0004003206,0.0003839113,0.0014567,0.0002021674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002766718,"about_ca_system_score_gemma":0.0002120824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004536998,"about_ca_topic_score_gemma":0.0013337,"domain_scores_codex":[0.9994411,0.0003304652,0.00004075157,0.00007202273,0.00004546421,0.00007012215],"domain_scores_gemma":[0.9993199,0.0002310806,0.0002063091,0.00005217614,0.00003279499,0.0001577282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.918071,0.001786653,0.02361734,0.001044349,0.005226508,0.00009492826,0.00007036274,0.0009614787,0.003744954,0.00024827,0.001342156,0.043792],"study_design_scores_gemma":[0.7157747,0.1038957,0.1624773,0.0003936983,0.009590608,0.0003286184,0.0001189334,0.002705042,0.001058266,0.0007387327,0.002852031,0.00006641306],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891636,0.008281836,0.0001518345,0.000464631,0.0001119248,0.000168786,0.0004403027,0.00002111742,0.001195911],"genre_scores_gemma":[0.995981,0.001667346,0.0003029832,0.0004956683,0.0001909761,0.0001415716,0.0008321275,0.000004902197,0.0003835114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001597632,"threshold_uncertainty_score":0.006714344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03824252262840183,"score_gpt":0.2922582630208994,"score_spread":0.2540157403924975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}