{"id":"W4313490241","doi":"10.1101/2023.01.04.522740","title":"Indel driven rapid evolution of core nuclear pore protein gene promoters","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Winnipeg","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Promoter; Indel; Biology; Gene; Genetics; Nuclear pore; Coding region; Gene expression; Cytoplasm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001941637,0.0002125385,0.0002455075,0.0004285543,0.0001845544,0.0003529551,0.0002695748,0.0003582281,0.001712559],"category_scores_gemma":[0.0005939039,0.0002303843,0.0002371982,0.0002398494,0.0003042348,0.0002227882,0.0005688003,0.0009393458,0.0008237302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002710417,"about_ca_system_score_gemma":0.0001308273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001985046,"about_ca_topic_score_gemma":0.0003571279,"domain_scores_codex":[0.9998252,0.00002023051,0.000009265013,0.00006266837,0.000053243,0.0000293825],"domain_scores_gemma":[0.9994248,0.0001959209,0.0001512936,0.00008718633,0.00006802964,0.00007281259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007472483,0.00001786498,0.001286449,0.00002801505,0.000008037791,0.0002088967,0.00003040851,0.0003907093,0.9949796,0.0002526217,0.00005147217,0.002671276],"study_design_scores_gemma":[0.00003401818,0.0001770611,0.03876786,0.00002352091,0.00003121433,0.001988205,0.00008860283,0.009390724,0.9424639,0.001407364,0.005594856,0.00003260138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859248,0.0003857026,0.01114508,0.00006763577,0.00003367909,0.00002234027,0.0004694135,0.0003190487,0.001632255],"genre_scores_gemma":[0.9913258,0.0002136354,0.004843554,0.00009774263,0.00001998672,0.00002617838,0.0008964413,0.0002146178,0.002362026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001712559,"threshold_uncertainty_score":0.005729079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01962185708713821,"score_gpt":0.2366242159217643,"score_spread":0.2170023588346261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}