{"id":"W4313537466","doi":"10.1016/j.molstruc.2023.134924","title":"Design, synthesis, in vitro anti-oxidant evaluation, α-amylase inhibition assay, and molecular docking analysis of 2-(2-benzylidenehydrazinyl)-4,4-diphenyl-1H-imidazol-5(4H)-ones","year":2023,"lang":"en","type":"article","venue":"Journal of Molecular Structure","topic":"Synthesis and Characterization of Heterocyclic Compounds","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Laurentian University","funders":"","keywords":"Chemistry; DPPH; Acarbose; Amylase; Docking (animal); IC50; In vitro; Enzyme; Antioxidant; Combinatorial chemistry; Biochemistry; Stereochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001495089,0.0004197745,0.0003732935,0.0003286247,0.0001933304,0.0003119171,0.0006091468,0.0002104031,0.001333374],"category_scores_gemma":[0.00009102911,0.0002102446,0.0002899512,0.0002413011,0.0001364357,0.0002260362,0.0001562475,0.0003665026,0.0005487674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002945564,"about_ca_system_score_gemma":0.0003762677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000547166,"about_ca_topic_score_gemma":0.001819569,"domain_scores_codex":[0.9999242,0.000007921264,0.000006922477,0.000018784,0.00002298597,0.00001916267],"domain_scores_gemma":[0.999949,0.000003017195,0.00001818945,0.00000587252,0.00001244947,0.00001147899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005225813,0.0003664548,0.0003401008,0.000533237,0.0000414627,0.0002140433,0.00004567854,0.004709283,0.9647489,0.001379055,0.0005091374,0.02659013],"study_design_scores_gemma":[0.0002635116,0.005072072,0.001766475,0.00003679647,0.0001302445,0.00028832,0.00004050099,0.007287009,0.9690514,0.0001864789,0.01583873,0.0000386013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9433014,0.01065193,0.03256545,0.0003909569,0.0001687862,0.001000451,0.001874992,0.0003723194,0.009673657],"genre_scores_gemma":[0.9600712,0.007850477,0.02209329,0.0001260686,0.00002017918,0.0004938896,0.001071381,0.00003023467,0.008243355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001333374,"threshold_uncertainty_score":0.004460633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01332684443769454,"score_gpt":0.2573827780575129,"score_spread":0.2440559336198184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}