{"id":"W4313543655","doi":"10.1002/iub.2700","title":"The roles of proteases in prostate cancer","year":2023,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital; University of Calgary","funders":"National Cancer Institute; Advance Queensland; Medical Research Council; National Institutes of Health; Canadian Institutes of Health Research; Sigrid Juséliuksen Säätiö; Magnus Ehrnroothin Säätiö; Suomen kliinisen kemian yhdistys; Deutsche Forschungsgemeinschaft; Helsingin ja Uudenmaan Sairaanhoitopiiri; National Institute of General Medical Sciences; Bundesministerium für Bildung und Forschung; Prostate Cancer Fight Foundation; National Health and Medical Research Council; Academy of Finland; Prostate Cancer Canada","keywords":"Proteases; Cancer; Prostate cancer; Prostate; Cancer research; Medicine; Biology; Internal medicine; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002648741,0.0002131563,0.0004909162,0.00004745908,0.00004650936,0.00001700286,0.0002915334,0.0001809936,0.000004781476],"category_scores_gemma":[0.0002196359,0.0001345208,0.0002162985,0.0001591252,0.00005482015,0.00000154437,0.0001622892,0.0001443894,0.00001818141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001574387,"about_ca_system_score_gemma":0.0006217253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004967716,"about_ca_topic_score_gemma":0.0002138228,"domain_scores_codex":[0.9987875,0.0001231396,0.0004303985,0.0002866619,0.0001324333,0.0002399151],"domain_scores_gemma":[0.9992472,0.00002392386,0.0002577335,0.0003682259,0.00004351734,0.00005943439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005748685,0.00007311773,0.00001483449,0.01099528,0.0003269749,0.00001511097,0.0000390587,0.000004007275,0.001777523,0.0002677348,0.009101612,0.9773273],"study_design_scores_gemma":[0.0001069151,0.00006725192,7.879351e-7,0.003751072,0.00006072714,0.000001983171,0.00001724961,9.326912e-7,0.005972849,0.00009228312,0.9897624,0.0001655754],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001996926,0.9981314,0.000001864812,0.00003719678,0.0001760683,0.001182045,0.0001615102,0.00001083132,0.00009942585],"genre_scores_gemma":[0.0001138952,0.9968069,0.0000113107,0.00003503043,0.0003571611,0.001395593,0.00008650376,0.00004834636,0.001145243],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9806607,"threshold_uncertainty_score":0.54856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03779600965642404,"score_gpt":0.340403845073296,"score_spread":0.302607835416872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}