{"id":"W4313545063","doi":"10.1128/aac.01346-22","title":"<i>In Vitro</i> Activity of Ceftibuten-Avibactam against β-Lactamase-Positive Enterobacterales from the ATLAS Global Surveillance Program","year":2023,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Pfizer","keywords":"Avibactam; Cephalosporin; Prodrug; Ceftazidime/avibactam; Medicine; Carbapenem; Urinary system; In vitro; Microbiology; Antibiotics; Chemistry; Pharmacology; Enterobacteriaceae; Biology; Internal medicine; Escherichia coli; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004948037,0.0004796028,0.0003378034,0.000490936,0.0001774481,0.0003629937,0.0002037356,0.0002237005,0.0007007035],"category_scores_gemma":[0.000406402,0.0001342401,0.0004100372,0.0005901955,0.0002125037,0.0001753957,0.0001984752,0.0003119947,0.0002791077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001900989,"about_ca_system_score_gemma":0.0003265478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003457172,"about_ca_topic_score_gemma":0.00325453,"domain_scores_codex":[0.9994181,0.000212781,0.00009063601,0.00005730577,0.0001450897,0.00007600895],"domain_scores_gemma":[0.9997616,0.00006196758,0.00004267817,0.00002111345,0.00008168309,0.00003097592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000937559,0.0004078127,0.007925089,0.0001448509,0.00004887686,0.0001433494,0.00007518035,0.0005466658,0.9846243,0.00005308427,0.0001969394,0.004896354],"study_design_scores_gemma":[0.0000376961,0.005138826,0.0385246,0.00001565679,0.00006965378,0.0005943665,0.0001101959,0.0006213078,0.9532883,0.00002577163,0.001561868,0.00001170271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941986,0.002343555,0.0005531619,0.00007031926,0.00003090752,0.00005403961,0.001139745,0.00001719147,0.001592568],"genre_scores_gemma":[0.9923925,0.001401499,0.002098514,0.00006212359,0.00002437941,0.00002335084,0.003181464,0.000008534335,0.0008076992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003457172,"threshold_uncertainty_score":0.006874084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007319971851342717,"score_gpt":0.2542022183484027,"score_spread":0.24688224649706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}