{"id":"W4313584784","doi":"10.3390/cells12010136","title":"Human Neutrophils Generate Extracellular Vesicles That Modulate Their Functional Responses","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Neutrophil extracellular traps; Chemokine; Innate immune system; Cell biology; Autocrine signalling; Paracrine signalling; Extracellular; Immune system; Inflammation; Immunology; Biology; Chemotaxis; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002144481,0.0001833697,0.000130421,0.00007219648,0.00006564236,0.0002763823,0.00007052209,0.0002059108,0.0009549032],"category_scores_gemma":[0.0001671104,0.0000591463,0.0001054385,0.00006155814,0.00008554482,0.0001845442,0.0002342387,0.0001849019,0.0003165078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001229814,"about_ca_system_score_gemma":0.0000663269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001200925,"about_ca_topic_score_gemma":0.0001545475,"domain_scores_codex":[0.9998753,0.00004089017,0.00001099342,0.0000207714,0.00002655978,0.00002549267],"domain_scores_gemma":[0.9999605,0.00001095034,0.000009754413,0.000006169487,0.000006894957,0.000005593241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002179811,0.00002102273,0.0006476755,0.00004669153,0.000003745001,0.00005835773,0.00003311212,0.00006143195,0.9952942,0.0001802547,0.00005826264,0.003377213],"study_design_scores_gemma":[0.00003519035,0.000521996,0.008802688,0.00001870037,0.00001232184,0.0005438455,0.00007497867,0.0005883856,0.982455,0.000125243,0.00681567,0.000006166632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889895,0.005134336,0.003712661,0.000101162,0.0000279883,0.0000707943,0.0003158301,0.00002071987,0.00162703],"genre_scores_gemma":[0.9959437,0.0009462095,0.001455497,0.00004651407,0.000007266988,0.0000301997,0.0002920635,0.00000377505,0.00127476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009549032,"threshold_uncertainty_score":0.003194451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04036900300097089,"score_gpt":0.2268171304937372,"score_spread":0.1864481274927663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}