{"id":"W4313584784","doi":"10.3390/cells12010136","title":"Human Neutrophils Generate Extracellular Vesicles That Modulate Their Functional Responses","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Neutrophil extracellular traps; Chemokine; Innate immune system; Cell biology; Autocrine signalling; Paracrine signalling; Extracellular; Immune system; Inflammation; Immunology; Biology; Chemotaxis; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003689867,0.0002771976,0.0002909342,0.0001672753,0.001189829,0.0000304253,0.0003312843,0.0001085326,0.006780444],"category_scores_gemma":[0.00000423581,0.0002484796,0.0001613719,0.0001595307,0.0001552321,0.0001008205,0.0002941925,0.0004738446,0.0006707459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007024037,"about_ca_system_score_gemma":0.00005265276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000176611,"about_ca_topic_score_gemma":0.000001732409,"domain_scores_codex":[0.9980063,0.0006770552,0.0002663711,0.0005096484,0.00007755723,0.0004630117],"domain_scores_gemma":[0.9992596,0.00007825869,0.0001386213,0.0004420241,0.00004324373,0.00003827849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000188378,0.0001454968,0.00004636265,0.000005527188,0.0001092793,0.00005724923,0.0001907588,0.0004292571,0.9891612,0.003866735,0.005120253,0.0006794952],"study_design_scores_gemma":[0.0008023505,0.000255778,0.001121294,0.000004354532,0.00002666077,0.00006134107,0.0002873666,0.000008159712,0.8987669,0.001408464,0.0969874,0.0002699005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935834,0.003501609,0.0002805387,0.000301236,0.001400088,0.0002608635,0.0001745689,0.0001249386,0.0003726933],"genre_scores_gemma":[0.9688458,0.00004064435,0.00005045216,0.0005254744,0.00010288,0.00008645708,0.000229102,0.00004385932,0.03007527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09186714,"threshold_uncertainty_score":0.9999967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04036900300097089,"score_gpt":0.2268171304937372,"score_spread":0.1864481274927663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}