{"id":"W4313585009","doi":"10.3390/ijms24010727","title":"Reovirus μ2 Protein Impairs Translation to Reduce U5 snRNP Protein Levels","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"snRNP; RNA splicing; Biology; Cell biology; RNA-binding protein; RNA; Translation (biology); Messenger RNA; Molecular biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001404577,0.0005089957,0.0002362698,0.0002283612,0.0001240632,0.0003083719,0.0002799779,0.0003349702,0.001237657],"category_scores_gemma":[0.000105919,0.0001350714,0.0003434557,0.0001075225,0.000187933,0.0001447714,0.0001992272,0.0005563492,0.0003273252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000377486,"about_ca_system_score_gemma":0.0001837998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009391404,"about_ca_topic_score_gemma":0.000872592,"domain_scores_codex":[0.9998123,0.0000305584,0.00001922015,0.00004376186,0.00005469617,0.00003955701],"domain_scores_gemma":[0.9999171,0.00001628128,0.00001898167,0.00001377543,0.00000950264,0.00002428079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005524976,0.00002060622,0.00006671407,0.00001806366,0.000005526617,0.00002315477,0.00000439813,0.00001876279,0.9994152,0.00004062309,0.00002803446,0.0003038117],"study_design_scores_gemma":[0.000008185477,0.0002718833,0.001635023,0.000004447664,0.00001384639,0.0001542439,0.00001455702,0.0005072617,0.9956408,0.00002507239,0.001721269,0.00000331364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908562,0.002647215,0.003565901,0.0001448288,0.0001386186,0.00002891464,0.0004863474,0.0001702969,0.001961761],"genre_scores_gemma":[0.9915873,0.0008387084,0.001756147,0.0001005891,0.00002158243,0.00003087301,0.0008328555,0.00004104294,0.004790765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001237657,"threshold_uncertainty_score":0.004140377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03386519297544509,"score_gpt":0.3385622439649273,"score_spread":0.3046970509894822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}