{"id":"W4313596242","doi":"10.1002/jsp2.1240","title":"Dynamic loading leads to increased metabolic activity and spatial redistribution of viable cell density in nucleus pulposus tissue","year":2023,"lang":"en","type":"article","venue":"JOR Spine","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Horizon 2020 Framework Programme; European Commission; H2020 European Research Council; Arthritis Society; Dutch Arthritis Society","keywords":"Extracellular; Lactate dehydrogenase; Chemistry; Metabolism; Cell; Biophysics; Staining; Glycolysis; Nucleus; Extracellular matrix; Cell growth; Biochemistry; Cell biology; Biology; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001435632,0.0002125819,0.0002908552,0.0001706603,0.0001430858,0.0003606103,0.0001717064,0.0001855758,0.0009608123],"category_scores_gemma":[0.0001621157,0.0001357053,0.0001259651,0.0001282139,0.0003407157,0.000252185,0.0003092191,0.0002916355,0.0001459761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001997101,"about_ca_system_score_gemma":0.0001888909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007074252,"about_ca_topic_score_gemma":0.0007056984,"domain_scores_codex":[0.9998092,0.00001964862,0.00002248141,0.00004926625,0.00006477434,0.00003469889],"domain_scores_gemma":[0.9998618,0.00004081505,0.00003612294,0.00001188917,0.00002053063,0.0000288773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001781906,0.0000341891,0.0004481932,0.00003447802,0.000002652738,0.00007433381,0.00005256629,0.00005692244,0.9976549,0.00002159856,0.00001000135,0.001432004],"study_design_scores_gemma":[0.00001032096,0.0009340872,0.01874119,0.00001652681,0.0000205776,0.0003312928,0.0003242849,0.001283329,0.9771817,0.00007390743,0.001073171,0.000009537456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970686,0.0006306509,0.001635699,0.00002141329,0.000013218,0.000007824926,0.00003703822,0.00001035255,0.0005752841],"genre_scores_gemma":[0.9979643,0.0002496689,0.0009141982,0.00001770202,0.000004967485,0.00002630804,0.00006793591,0.000005865461,0.0007489829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009608123,"threshold_uncertainty_score":0.0032143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007991875216413105,"score_gpt":0.2723091231390736,"score_spread":0.2643172479226605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}