{"id":"W4313612142","doi":"10.1021/acs.inorgchem.2c03671","title":"Comparative Study of a Decadentate Acyclic Chelate, HOPO-O<sub>10</sub>, and Its Octadentate Analogue, HOPO-O<sub>8</sub>, for Radiopharmaceutical Applications","year":2023,"lang":"en","type":"article","venue":"Inorganic Chemistry","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; TRIUMF; University of Manitoba; Simon Fraser University","funders":"National Research Council Canada; China Postdoctoral Science Foundation; Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Chelation; Chemistry; Ligand (biochemistry); Combinatorial chemistry; Radiochemistry; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002713456,0.0004912799,0.0008643402,0.00009663532,0.0002828964,0.00004506805,0.0003712077,0.0002903368,0.00009988111],"category_scores_gemma":[0.0001043287,0.0005138489,0.0001965863,0.001285039,0.0003072507,0.000121288,0.0001973682,0.0006655506,0.0001531836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001614574,"about_ca_system_score_gemma":0.0001656027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003005222,"about_ca_topic_score_gemma":0.000002108135,"domain_scores_codex":[0.9970003,0.00004203602,0.0008863495,0.0009459193,0.0004689698,0.0006563747],"domain_scores_gemma":[0.9977859,0.0003945284,0.000288612,0.0005997809,0.0002664184,0.0006647757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003170717,0.001048285,0.0006224399,0.0007845581,0.0004556798,0.00002878231,0.0005545517,0.00001555334,0.9939086,0.00001725676,0.001622336,0.0006248337],"study_design_scores_gemma":[0.005448401,0.0001217425,0.002217472,0.00006858852,0.0008300928,0.000184999,0.001339416,0.001119482,0.9868707,0.0001056757,0.001257632,0.0004357675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951422,0.0007004541,0.0001123966,0.0006901489,0.00003741962,0.002319755,0.0002543965,0.0002919686,0.0004512119],"genre_scores_gemma":[0.9967396,0.0007115491,0.00004248838,0.0001109457,0.000332937,0.001263081,0.0004521793,0.00007534208,0.0002718948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00703792,"threshold_uncertainty_score":0.9997313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05177507711073253,"score_gpt":0.3690720608683085,"score_spread":0.3172969837575759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}