{"id":"W4313612142","doi":"10.1021/acs.inorgchem.2c03671","title":"Comparative Study of a Decadentate Acyclic Chelate, HOPO-O<sub>10</sub>, and Its Octadentate Analogue, HOPO-O<sub>8</sub>, for Radiopharmaceutical Applications","year":2023,"lang":"en","type":"article","venue":"Inorganic Chemistry","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; TRIUMF; University of Manitoba; Simon Fraser University","funders":"National Research Council Canada; China Postdoctoral Science Foundation; Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Chelation; Chemistry; Ligand (biochemistry); Combinatorial chemistry; Radiochemistry; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007817519,0.0001453612,0.0001053705,0.0001044867,0.00006156823,0.0001318431,0.0001047135,0.0001147727,0.0009252535],"category_scores_gemma":[0.0001814896,0.00005883589,0.00007713088,0.0001006777,0.0001062969,0.0001257486,0.00008552876,0.00007315452,0.0001223751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000116982,"about_ca_system_score_gemma":0.0001804725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004570152,"about_ca_topic_score_gemma":0.0008844252,"domain_scores_codex":[0.9999592,0.000005265814,0.000003855044,0.0000109217,0.00001013428,0.00001061357],"domain_scores_gemma":[0.9999126,0.00001683456,0.00002750491,0.000004128202,0.00001756125,0.00002131439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006547213,0.00003353989,0.0006304036,0.0001744512,0.000009154643,0.00006550904,0.0000382195,0.0003651784,0.992402,0.0001598863,0.00007660032,0.005390457],"study_design_scores_gemma":[0.00002223579,0.001859352,0.003824914,0.00001132224,0.00003779723,0.0001555118,0.00004263443,0.0009109586,0.9860174,0.00002365875,0.007081828,0.00001229948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970834,0.0009619296,0.0003887781,0.0000114141,0.000007522987,0.000009953469,0.0001105145,0.00001239236,0.001414148],"genre_scores_gemma":[0.9960616,0.0008265373,0.00129825,0.00001743376,0.000004425671,0.00001046181,0.0002289223,0.000007819454,0.001544462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009252535,"threshold_uncertainty_score":0.003095269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05177507711073253,"score_gpt":0.3690720608683085,"score_spread":0.3172969837575759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}