{"id":"W4313640065","doi":"10.3389/fgene.2022.993687","title":"Coding roles of long non-coding RNAs in breast cancer: Emerging molecular diagnostic biomarkers and potential therapeutic targets with special reference to chemotherapy resistance","year":2023,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Epigenetics; microRNA; Breast cancer; DNA methylation; Biology; Cancer; Cancer research; Epigenetic therapy; Long non-coding RNA; Histone; Bioinformatics; Gene; Genetics; RNA; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003584146,0.0005333883,0.001070619,0.0006260101,0.00006197649,0.00004991776,0.0005367172,0.0004827745,0.00001030837],"category_scores_gemma":[0.00004941731,0.0005382739,0.0001508603,0.0008915052,0.0001534707,0.000005740835,0.0002502268,0.000418371,0.000001026007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002260231,"about_ca_system_score_gemma":0.0004855771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004092538,"about_ca_topic_score_gemma":0.0005673583,"domain_scores_codex":[0.9970739,0.0001932687,0.0006637514,0.0009454199,0.0004412802,0.0006824053],"domain_scores_gemma":[0.9988804,0.00003346239,0.000287711,0.0005304052,0.000110046,0.0001579785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006510334,0.00009672971,0.0003868097,0.006849126,0.001190794,0.0004295821,0.0002350512,0.001847209,0.01342014,0.00002090291,0.001200878,0.9736717],"study_design_scores_gemma":[0.0133324,0.001969464,0.004594046,0.1135457,0.003060119,0.0003688423,0.001915976,0.002337732,0.1253097,0.0005427996,0.7230777,0.009945526],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006386848,0.9289547,0.06829751,0.00008011454,0.0003860918,0.001362722,0.0001917567,0.00001090873,0.00007752304],"genre_scores_gemma":[0.004038466,0.9923315,0.002774096,0.00004425396,0.0002273252,0.0002124139,0.0001231057,0.0001733265,0.00007552563],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9637262,"threshold_uncertainty_score":0.9997069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01348743150392273,"score_gpt":0.2954907424110702,"score_spread":0.2820033109071474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}