{"id":"W4313825693","doi":"10.1016/j.celrep.2023.111998","title":"Spike recognition and neutralization of SARS-CoV-2 Omicron subvariants elicited after the third dose of mRNA vaccine","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de Santé Publique du Québec; Héma-Québec; University of Ottawa; McGill University Health Centre; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Institute of Infection and Immunity; Canadian Institutes of Health Research; Mitacs; Fondation du CHUM; Canada Foundation for Innovation; Canada Research Chairs; Pfizer; Cooley's Anemia Foundation","keywords":"Neutralization; Vaccination; Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Immunology; Humoral immunity; Biology; Messenger RNA; Immunity; Antibody; Immune system; Coronavirus disease 2019 (COVID-19); Medicine; Virus; Gene; Genetics; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000237207,0.0003140509,0.0003630569,0.0001351899,0.0001604854,0.000273658,0.0001032591,0.0003052532,0.001024418],"category_scores_gemma":[0.0003605364,0.0001117313,0.0002767472,0.00006833914,0.0001582547,0.0001749576,0.0001790249,0.0006449294,0.0002677209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001379905,"about_ca_system_score_gemma":0.0001275263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006363507,"about_ca_topic_score_gemma":0.0004178848,"domain_scores_codex":[0.9997986,0.0000337025,0.00001071731,0.00003704691,0.00004418329,0.00007571442],"domain_scores_gemma":[0.9998004,0.00005002537,0.00003218258,0.00002352889,0.00004278301,0.0000511339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001075242,0.0005975402,0.005900883,0.00002827727,0.00002715929,0.00009873325,0.0002052633,0.0001554295,0.9868667,0.00004077667,0.0001241635,0.004879742],"study_design_scores_gemma":[0.0003420636,0.06240135,0.2737305,0.0000285048,0.0001727581,0.001714178,0.0006789553,0.00441747,0.653345,0.0001921925,0.002948813,0.00002819714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995577,0.00004959587,0.0001310341,0.00001128577,0.0000110295,0.0000115195,0.00002984985,0.000004473754,0.0001935347],"genre_scores_gemma":[0.9990375,0.00003588076,0.0001050514,0.00005323343,0.00001035568,0.00001188574,0.0001470675,0.00000323254,0.0005957786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001024418,"threshold_uncertainty_score":0.003427029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05395636204710241,"score_gpt":0.3262836380279395,"score_spread":0.2723272759808371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}