{"id":"W4313826435","doi":"10.1242/dev.201013","title":"Actomyosin-mediated cellular tension promotes Yap nuclear translocation and myocardial proliferation through α5 integrin signaling","year":2023,"lang":"en","type":"article","venue":"Development","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Australian Research Council; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; Canada Research Chairs; National Institutes of Health; Brown University","keywords":"Biology; Cell biology; Cytokinesis; Contractility; Cell growth; Myosin light-chain kinase; Myosin; Myocyte; Cell; Cell division; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001070664,0.0002723329,0.0001081605,0.0001261914,0.0001348029,0.0001910469,0.0001151917,0.0001494997,0.001548776],"category_scores_gemma":[0.0000689481,0.0001204309,0.000165485,0.00006908902,0.0001991343,0.0001474759,0.0002006754,0.0003424296,0.0002723049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001779193,"about_ca_system_score_gemma":0.0001612423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003534624,"about_ca_topic_score_gemma":0.001062118,"domain_scores_codex":[0.9999012,0.00001504284,0.000006385597,0.00002184498,0.00002881448,0.00002661105],"domain_scores_gemma":[0.9999443,0.000005852282,0.00002265546,0.000004168843,0.000004613559,0.00001832881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002831055,0.000004551503,0.0001261321,0.00001223545,0.000001301659,0.00003133509,0.000006559655,0.00001531031,0.9992847,0.0001069666,0.00001749827,0.0003650674],"study_design_scores_gemma":[0.00001726446,0.0001243838,0.01102332,0.000007229468,0.00001025488,0.0002406783,0.00004014056,0.0009006821,0.9852939,0.00007212386,0.002267425,0.000002598739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994428,0.0006986509,0.002590731,0.00009255395,0.00001367752,0.000008180755,0.0001236563,0.00004661243,0.001997805],"genre_scores_gemma":[0.9955516,0.0004405864,0.0009040568,0.00002942101,0.000006658555,0.00001829407,0.0001862755,0.00001147104,0.002851562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001548776,"threshold_uncertainty_score":0.005181134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01841194493799408,"score_gpt":0.2511905912037239,"score_spread":0.2327786462657299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}