{"id":"W4313829768","doi":"10.1093/evolut/qpac028","title":"Genome-wide DNA methylation predicts environmentally driven life history variation in a marine fish","year":2022,"lang":"en","type":"article","venue":"Evolution","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi; Memorial University of Newfoundland; University of Calgary; Bedford Institute of Oceanography; Fisheries and Oceans Canada; Université Laval","funders":"Fisheries and Oceans Canada; Natural Sciences and Engineering Research Council of Canada; World Wildlife Fund; Department of Fisheries and Aquaculture, Government of Newfoundland and Labrador; National Science Foundation","keywords":"Biology; Epigenetics; DNA methylation; Capelin; Genetics; Evolutionary biology; Genome; Genetic variation; Epigenomics; Ecology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003637664,0.0001020724,0.00009260664,0.0001058907,0.0000950523,0.00000587769,0.0001060786,0.00008281456,0.0002731588],"category_scores_gemma":[0.0001054814,0.00013622,0.00004951621,0.00008915373,0.00002431034,0.000008992803,0.0001883418,0.0001114709,0.00000667145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007038647,"about_ca_system_score_gemma":0.0001121819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008510703,"about_ca_topic_score_gemma":0.0000873102,"domain_scores_codex":[0.9988591,0.0001969282,0.0002472032,0.0003097077,0.0002241059,0.0001629535],"domain_scores_gemma":[0.9995571,0.00001326779,0.0001365496,0.0002172522,0.00001914373,0.00005664796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007903082,0.000121288,0.05704997,0.000007419437,0.00001974795,0.000001269653,0.000215678,0.02455024,0.9170574,0.00006271379,0.0002829036,0.0005523383],"study_design_scores_gemma":[0.000596963,0.0002403392,0.9445757,0.00000148319,0.00001404187,7.82573e-7,0.00003785023,0.001975287,0.00456143,0.0003296598,0.04751073,0.0001556976],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897022,0.0007672058,0.007714407,0.0001780656,0.0002798074,0.0002752293,0.00001865229,0.00001416244,0.001050297],"genre_scores_gemma":[0.9974704,0.0001081673,0.0005256131,0.0001808778,0.0001475505,0.00009181333,0.0009251037,0.00001927041,0.0005311831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.912496,"threshold_uncertainty_score":0.5554889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00808751110163489,"score_gpt":0.1936684899632391,"score_spread":0.1855809788616042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}