{"id":"W4313830852","doi":"10.1038/s41588-022-01254-1","title":"Single-cell transcriptomic analysis of endometriosis","year":2023,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Endometriosis Research and Treatment","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia; University of British Columbia Hospital","funders":"Clinical and Translational Science Institute, University of California, Los Angeles; National Institute of Biomedical Imaging and Bioengineering; Michael Smith Health Research BC; Canadian Cancer Society Research Institute; U.S. Department of Health and Human Services; National Institutes of Health; National Center for Advancing Translational Sciences; BC Cancer Foundation; Cedars-Sinai Medical Center; Government of Canada; Ovarian Cancer Research Alliance; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; American Cancer Society","keywords":"Stromal cell; Endometriosis; Biology; Epithelium; Stroma; Cancer research; Downregulation and upregulation; Cell type; Transcriptome; Endometrium; Somatic cell; Pathology; Cell; Endocrinology; Immunology; Medicine; Genetics; Immunohistochemistry; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001432039,0.0001363753,0.0004027867,0.000350595,0.0002948778,0.0005780259,0.0001780501,0.0003630087,0.001324874],"category_scores_gemma":[0.0002808952,0.0001362698,0.0003808453,0.0004216356,0.0001814819,0.000206341,0.0003135091,0.000462958,0.0004899279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002024568,"about_ca_system_score_gemma":0.0002091458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006556432,"about_ca_topic_score_gemma":0.002340809,"domain_scores_codex":[0.9998704,0.00001003174,0.000006713013,0.00004790489,0.00004029479,0.00002464717],"domain_scores_gemma":[0.999904,0.00003464564,0.00001301362,0.00001310801,0.00001985861,0.00001527374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008464324,0.00000825748,0.002163735,0.0001002037,0.00002853781,0.00007501257,0.00004443144,0.0003515524,0.9925648,0.000198944,0.0003671617,0.004012812],"study_design_scores_gemma":[0.00005138014,0.0004136347,0.3375528,0.000080487,0.0002247761,0.001479007,0.0009968287,0.02310847,0.602347,0.002168574,0.03149897,0.00007818101],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9553337,0.004120296,0.01779422,0.0004715859,0.000204148,0.00006751638,0.01784719,0.0002602151,0.003901167],"genre_scores_gemma":[0.9639132,0.002760658,0.0140333,0.0004505436,0.00006785663,0.0001258297,0.01484841,0.0001169121,0.003683186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001324874,"threshold_uncertainty_score":0.004432082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02719875744248442,"score_gpt":0.3149313678337523,"score_spread":0.2877326103912679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}