{"id":"W4313893282","doi":"10.1016/j.modpat.2022.100010","title":"p53-Abnormal “Fields of Dysplasia” in Human Papillomavirus–Independent Vulvar Squamous Cell Carcinoma Impacts Margins and Recurrence Risk","year":2023,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Association of Nurses in Oncology; University of British Columbia; Vancouver General Hospital","funders":"","keywords":"Carcinoma in situ; Pathology; Immunohistochemistry; Vulvar intraepithelial neoplasia; Dysplasia; Vulvar Carcinoma; Intraepithelial neoplasia; Lichen sclerosus; Staining; Biology; Carcinoma; Medicine; Vulva; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005562775,0.0001663197,0.0004367893,0.0003283856,0.00007363981,0.00000938237,0.0001390941,0.0002445885,0.0003573458],"category_scores_gemma":[0.0001140589,0.0001505124,0.00006397265,0.0002998263,0.000163953,0.00005196208,0.0002148578,0.0006375072,0.0000316883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006829826,"about_ca_system_score_gemma":0.0001041106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009928456,"about_ca_topic_score_gemma":0.001319196,"domain_scores_codex":[0.9982114,0.000160925,0.0003446529,0.0004174971,0.0003174562,0.0005480539],"domain_scores_gemma":[0.9991336,0.000126788,0.0000811362,0.0003670178,0.00008161327,0.0002098136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006389798,0.0003002247,0.9479694,0.0005620026,0.000009758083,0.002380323,0.003870073,0.00007425698,0.02382437,0.0001503591,0.0002802422,0.01994005],"study_design_scores_gemma":[0.002969663,0.001091537,0.9870184,0.00001193975,0.00003227649,0.0001106967,0.0001645163,0.001891175,0.005373521,0.001143033,0.0000584837,0.000134781],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992049,0.0008371305,0.0001329401,0.0002002925,0.00008378228,0.0003255024,0.0000570378,0.00003571886,0.006278636],"genre_scores_gemma":[0.9990388,0.0003283149,0.00003818248,0.00009387306,0.00006679118,0.00003094775,0.00003278796,0.00002336926,0.0003469893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03904902,"threshold_uncertainty_score":0.6137718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02827787007818603,"score_gpt":0.3152931613478636,"score_spread":0.2870152912696775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}