{"id":"W4315434918","doi":"10.1016/j.jtha.2023.01.003","title":"Platelet RNA sequencing for cancer screening in patients with unprovoked venous thromboembolism: a prospective cohort study","year":2023,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Trombosestichting Nederland","keywords":"Medicine; Internal medicine; Cancer; Prospective cohort study; Cohort; Receiver operating characteristic; Cohort study; Oncology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002505044,0.0003930799,0.0003775805,0.0004898765,0.000486794,0.0009836528,0.0005929461,0.0007342667,0.001467496],"category_scores_gemma":[0.00667769,0.0005043357,0.0007278954,0.0006624212,0.0002783312,0.0005452808,0.0005026399,0.0007902202,0.0002869813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002564342,"about_ca_system_score_gemma":0.0004184393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001894435,"about_ca_topic_score_gemma":0.002239499,"domain_scores_codex":[0.9984336,0.0006248105,0.0001173932,0.000409385,0.0002639933,0.0001508007],"domain_scores_gemma":[0.9962741,0.0008782432,0.001347661,0.0007098465,0.0004389077,0.0003512775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003752383,0.00004565849,0.99834,0.000009764263,0.0001097158,0.00009177038,0.00004548534,0.00002326747,0.0001665529,0.00001192856,0.00007450605,0.0007061249],"study_design_scores_gemma":[0.00006987509,0.0005013276,0.9972568,0.00001698488,0.000199974,0.0009966528,0.0001021656,0.0004610454,0.000113835,0.0000317424,0.0002405157,0.000009202833],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990441,0.0002827916,0.0001936248,0.0000283645,0.000006657743,0.00002512342,0.0002391924,0.000003421283,0.0001767614],"genre_scores_gemma":[0.9994568,0.00009522132,0.0001430594,0.00002471221,0.00001016256,0.00001669896,0.0001939636,0.000002439742,0.00005696372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002505044,"threshold_uncertainty_score":0.01324815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0281284372393295,"score_gpt":0.2981858394486827,"score_spread":0.2700574022093532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}