{"id":"W4315487318","doi":"10.3389/fcell.2022.1115903","title":"The MOZ-BRPF1 acetyltransferase complex in epigenetic crosstalk linked to gene regulation, development, and human diseases","year":2023,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Instrumentariumin Tiedesäätiö","keywords":"Crosstalk; Epigenetics; Histone acetyltransferase; Biology; Genetics; Gene; Regulation of gene expression; Acetyltransferase; Cell biology; Computational biology; Acetylation; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003339741,0.0007425202,0.0008892578,0.001929954,0.0002572879,0.0007824659,0.0006099215,0.0009118936,0.006178345],"category_scores_gemma":[0.0004331882,0.0002149015,0.0003784744,0.001890806,0.0002983493,0.001015591,0.0007051552,0.001300559,0.003961196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006669082,"about_ca_system_score_gemma":0.0009512628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008421752,"about_ca_topic_score_gemma":0.001459773,"domain_scores_codex":[0.9998953,0.00001485477,0.00001471687,0.00002069565,0.00003987121,0.00001457299],"domain_scores_gemma":[0.9998587,0.00005133512,0.00001993658,0.000005160314,0.00004270964,0.00002213337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009177961,0.00004712264,0.0001579151,0.0117433,0.0000756666,0.0003090486,0.00004703164,0.0003216682,0.003675738,0.00404272,0.05027427,0.9292138],"study_design_scores_gemma":[0.000007530736,0.00004127768,0.0004445901,0.001173669,0.00005722434,0.001234356,0.00002107442,0.00005140781,0.0004733244,0.001078924,0.9954069,0.000009702579],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001501417,0.9966205,0.0002447393,0.0003588059,0.0003871332,0.000005646093,0.00004032201,0.00002035761,0.002172312],"genre_scores_gemma":[0.0007217834,0.9967678,0.0002618685,0.0002449801,0.0002132766,0.000006542596,0.00007835874,0.000004339413,0.001701178],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006178345,"threshold_uncertainty_score":0.02066863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03717377120718544,"score_gpt":0.3111798194253177,"score_spread":0.2740060482181323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}