{"id":"W4315621681","doi":"10.21203/rs.3.rs-2183355/v1","title":"DNA-bridging by an archaeal histone variant via a unique tetramerisation interface","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Discovery Centre","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; University of Exeter","keywords":"Histone; Histone octamer; Nucleosome; Biology; DNA; Genetics; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001584173,0.0001833341,0.0001988543,0.0001056232,0.0003276802,0.0004583198,0.0005195541,0.0004759054,0.00265725],"category_scores_gemma":[0.0002743783,0.0002272136,0.0002162583,0.0001526954,0.0002708017,0.0004510434,0.0004366481,0.0006088176,0.0006979656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002566969,"about_ca_system_score_gemma":0.000128918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003672003,"about_ca_topic_score_gemma":0.0003699555,"domain_scores_codex":[0.9999167,0.000009763691,0.000004894739,0.00003244384,0.0000157969,0.00002040112],"domain_scores_gemma":[0.9997944,0.00003937403,0.00003321591,0.00005124646,0.0000174345,0.00006428156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003499636,0.00004999981,0.00064183,0.00004317803,0.00001526357,0.0003121921,0.0001023558,0.0004275441,0.9919813,0.002488526,0.0001624437,0.003425499],"study_design_scores_gemma":[0.00006074447,0.0003094925,0.003737519,0.00001149379,0.00002721884,0.000602102,0.0001788733,0.007174321,0.9820895,0.001031374,0.004750181,0.00002726914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900454,0.0002952362,0.00730924,0.00009716611,0.00004218883,0.000009624436,0.00005279022,0.0001420569,0.002006397],"genre_scores_gemma":[0.996566,0.00007056594,0.001879884,0.00004014304,0.000006443864,0.000004579409,0.00005989071,0.00002279025,0.001349864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00265725,"threshold_uncertainty_score":0.008889437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05035803054040634,"score_gpt":0.3866510939526765,"score_spread":0.3362930634122702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}