{"id":"W4315628354","doi":"10.3390/bioengineering10010093","title":"In Vitro 3D Modeling of Neurodegenerative Diseases","year":2023,"lang":"en","type":"review","venue":"Bioengineering","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Ataxia Foundation","keywords":"Neuroscience; Amyotrophic lateral sclerosis; Embryonic stem cell; Biology; Disease; Nervous system; Neural stem cell; Huntington's disease; Central nervous system; Stem cell; Medicine; Cell biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005991137,0.0009910166,0.001115479,0.001934948,0.000198823,0.001078823,0.0009790149,0.001144927,0.002267905],"category_scores_gemma":[0.0004178472,0.0004269972,0.0007648319,0.001261514,0.0003972591,0.0008283395,0.0007040875,0.0009784787,0.001871633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005545027,"about_ca_system_score_gemma":0.000597164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001180665,"about_ca_topic_score_gemma":0.001292996,"domain_scores_codex":[0.9997277,0.0000496513,0.00002706005,0.00003659961,0.0001367579,0.00002219453],"domain_scores_gemma":[0.9998552,0.0000683991,0.00002303488,0.000007702182,0.00003689774,0.000008800297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007247662,0.0001139519,0.0001933624,0.02251839,0.0001354517,0.0005555979,0.0001717202,0.007653955,0.04596367,0.01707035,0.0195958,0.8859553],"study_design_scores_gemma":[0.00001322081,0.0001023806,0.0004760104,0.002038574,0.0001163438,0.001762035,0.00005124333,0.001870008,0.01782483,0.003114717,0.9725873,0.000043375],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009344705,0.9869605,0.006059909,0.0001764779,0.000240175,0.00002632684,0.00007906555,0.00006487253,0.005458131],"genre_scores_gemma":[0.005283834,0.989092,0.003038981,0.0001351587,0.00009082174,0.00003996002,0.0001224325,0.00001307185,0.00218376],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002267905,"threshold_uncertainty_score":0.007586896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07716295030149087,"score_gpt":0.3402420566289461,"score_spread":0.2630791063274552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}