{"id":"W4315628354","doi":"10.3390/bioengineering10010093","title":"In Vitro 3D Modeling of Neurodegenerative Diseases","year":2023,"lang":"en","type":"review","venue":"Bioengineering","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Ataxia Foundation","keywords":"Neuroscience; Amyotrophic lateral sclerosis; Embryonic stem cell; Biology; Disease; Nervous system; Neural stem cell; Huntington's disease; Central nervous system; Stem cell; Medicine; Cell biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002127629,0.0003829816,0.001191866,0.0008229989,0.00001415793,0.00002332466,0.0004343207,0.0002304349,0.00001366419],"category_scores_gemma":[0.0002845124,0.0003674583,0.0002374431,0.001099385,0.00003238874,0.00007135896,0.0001760404,0.0005755675,0.00006805047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001601511,"about_ca_system_score_gemma":0.00007491484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001285558,"about_ca_topic_score_gemma":8.374452e-7,"domain_scores_codex":[0.9980938,0.00003974127,0.0007097852,0.0003079159,0.0003491955,0.0004995618],"domain_scores_gemma":[0.9991657,0.0002618458,0.00004091904,0.000358869,0.00002733225,0.00014537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.000003164221,0.00002851987,5.97684e-7,0.09138557,0.0002311634,0.0001201632,0.00005090853,0.3838641,0.0003734711,0.00006238032,0.0001841755,0.5236958],"study_design_scores_gemma":[0.00008069897,0.000008154502,5.041462e-7,0.007258199,0.00007306735,0.00000388544,0.000003094166,0.8880409,0.00009449861,0.000008709437,0.1040472,0.0003810971],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003617121,0.9935045,0.004843375,0.000003030709,0.0006270326,0.0003494528,0.0001080541,0.0004325167,0.00009587234],"genre_scores_gemma":[0.0004185565,0.9978875,0.001044114,0.000001293553,0.0002301193,0.0001260329,0.00005263881,0.0001975908,0.00004214325],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5233147,"threshold_uncertainty_score":0.9998778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07716295030149087,"score_gpt":0.3402420566289461,"score_spread":0.2630791063274552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}