{"id":"W4315629922","doi":"10.21203/rs.3.rs-2424611/v1","title":"eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Reumatikerförbundet; Knut och Alice Wallenbergs Stiftelse; Vetenskapsrådet; Karolinska Institutet; European Commission","keywords":"Autophagy; Cell biology; Connective tissue; Apoptosis; Tissue repair; Wound healing; Programmed cell death; Biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000220821,0.0003336243,0.0005146553,0.0003347184,0.0002443323,0.000474136,0.0001933634,0.0004715664,0.002318094],"category_scores_gemma":[0.0001386697,0.0001254011,0.0004025399,0.0002183984,0.0002554503,0.0002543549,0.0002528679,0.000729339,0.0003390848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002377248,"about_ca_system_score_gemma":0.0002355361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008260986,"about_ca_topic_score_gemma":0.001120065,"domain_scores_codex":[0.9998585,0.0000183191,0.000007586826,0.00002706527,0.0000371039,0.00005142306],"domain_scores_gemma":[0.9999328,0.00001141793,0.00001458652,0.000008678898,0.00000954535,0.00002308991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002572721,0.000319514,0.0004871239,0.0001649176,0.00006583484,0.0001535449,0.00002561335,0.0001840166,0.9843729,0.0003112032,0.0006732774,0.01066933],"study_design_scores_gemma":[0.0002008828,0.000776858,0.006502459,0.00001699135,0.0001219183,0.0003687602,0.00004775233,0.0007207358,0.980134,0.0001910694,0.01090442,0.00001419943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842044,0.005826678,0.004078769,0.0004079942,0.0002353486,0.00003990258,0.001068557,0.000235905,0.003902479],"genre_scores_gemma":[0.9807264,0.002523758,0.002731473,0.0002141484,0.00009528469,0.000072312,0.001548538,0.0001489425,0.01193917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002318094,"threshold_uncertainty_score":0.007754743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06874856993297962,"score_gpt":0.3923172423854306,"score_spread":0.323568672452451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}