{"id":"W4315630467","doi":"10.1016/j.modpat.2022.100053","title":"Reply to Comment on HPV-independent, p53-Wild-type Vulvar Intraepithelial Neoplasia: A Review of Nomenclature and the Journey to Characterize Acanthotic Precursor Lesions of the Vulva","year":2023,"lang":"en","type":"review","venue":"Modern Pathology","topic":"Cancer and Skin Lesions","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Vulva; Vulvar intraepithelial neoplasia; Medicine; Pathology; Vulvar neoplasm; Dermatology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004011255,0.001007455,0.002639165,0.00230913,0.000951594,0.002365938,0.002458129,0.01408999,0.004407192],"category_scores_gemma":[0.01794235,0.0005964558,0.001501521,0.001702113,0.002509939,0.005463297,0.002112737,0.01809987,0.00607217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00220354,"about_ca_system_score_gemma":0.002889626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002874333,"about_ca_topic_score_gemma":0.004573254,"domain_scores_codex":[0.9976792,0.000473926,0.0005701687,0.0003764325,0.0007061833,0.0001941395],"domain_scores_gemma":[0.9895952,0.005729277,0.0009554141,0.0002224539,0.002847928,0.0006497494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005060182,0.000009499072,0.0001195724,0.0006970083,0.00002637879,0.0004349471,0.00008837081,0.00002815773,0.0001645128,0.000744787,0.9857567,0.01187947],"study_design_scores_gemma":[0.00007606272,0.00005152707,0.0006646804,0.001256625,0.00006995835,0.002502811,0.0002093943,0.00005629133,0.0002035996,0.001747197,0.9930958,0.0000659821],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.0001737433,0.06490938,0.0002329559,0.7294648,0.2042015,0.00002120197,0.0002552225,0.00005014507,0.0006908274],"genre_scores_gemma":[0.0009810708,0.03728323,0.0001835863,0.8177814,0.1416403,0.00004108061,0.00009240607,0.00003072253,0.001966116],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01408999,"threshold_uncertainty_score":0.02121383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07764573297282232,"score_gpt":0.357650025908146,"score_spread":0.2800042929353237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}