{"id":"W4315630467","doi":"10.1016/j.modpat.2022.100053","title":"Reply to Comment on HPV-independent, p53-Wild-type Vulvar Intraepithelial Neoplasia: A Review of Nomenclature and the Journey to Characterize Acanthotic Precursor Lesions of the Vulva","year":2023,"lang":"en","type":"review","venue":"Modern Pathology","topic":"Cancer and Skin Lesions","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Vulva; Vulvar intraepithelial neoplasia; Medicine; Pathology; Vulvar neoplasm; Dermatology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001309926,0.000482602,0.00302481,0.0002518203,0.0001370808,0.0000117166,0.0005845687,0.000364932,0.0001207411],"category_scores_gemma":[0.00133142,0.0002487953,0.0005483045,0.0005915877,0.0002305932,0.00001992024,0.0005336402,0.001165405,0.00004840953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001425238,"about_ca_system_score_gemma":0.0005443254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000712585,"about_ca_topic_score_gemma":0.00004420328,"domain_scores_codex":[0.996362,0.0008654384,0.001215299,0.0006585572,0.0004920914,0.0004066499],"domain_scores_gemma":[0.9967704,0.0006524345,0.000670061,0.00149033,0.0001944046,0.0002223015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001150893,0.0004623735,0.00002889408,0.0925431,0.0007644516,0.0004177215,0.005824782,0.00000264472,0.0001416859,0.00111947,0.04843432,0.8491096],"study_design_scores_gemma":[0.001150963,0.0008184902,0.0006171097,0.1084593,0.002588304,0.001508767,0.00002374397,0.000005036488,0.00001034373,0.0003066342,0.8842388,0.0002724688],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005599308,0.9561456,0.0001074494,0.03513361,0.001168164,0.005843833,0.0006041924,0.00003628207,0.0004008879],"genre_scores_gemma":[0.0003602089,0.9760405,0.0001394643,0.02184485,0.0002513917,0.0003297839,0.00006153904,0.00008428259,0.0008879254],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8488372,"threshold_uncertainty_score":0.9999964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07764573297282232,"score_gpt":0.357650025908146,"score_spread":0.2800042929353237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}