{"id":"W4315699728","doi":"10.1177/13524585221144742","title":"Plasma neurofilament light chain in children with relapsing MS receiving teriflunomide or placebo: A post hoc analysis of the randomized TERIKIDS trial","year":2023,"lang":"en","type":"article","venue":"Multiple Sclerosis Journal","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; NeuroRx Research (Canada)","funders":"Sanofi","keywords":"Teriflunomide; Medicine; Placebo; Multiple sclerosis; Post-hoc analysis; Internal medicine; Mallinckrodt; Lesion; Gastroenterology; Nuclear medicine; Surgery; Pathology; Immunology; Fingolimod","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004570773,0.0004684486,0.002079378,0.001755009,0.000514488,0.0001816091,0.0005265429,0.0001550483,0.0001876375],"category_scores_gemma":[0.006555904,0.0002517501,0.0009535953,0.003894825,0.0004134178,0.000223906,0.0003836415,0.001047256,0.00001042638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003652965,"about_ca_system_score_gemma":0.000338959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003177975,"about_ca_topic_score_gemma":0.0008724163,"domain_scores_codex":[0.9939914,0.001426644,0.001570098,0.0005986897,0.001487218,0.0009258877],"domain_scores_gemma":[0.9960687,0.001790196,0.0008024039,0.0006933986,0.0003262341,0.0003190444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6775302,0.0003845187,0.2399689,0.00004001963,0.004278539,0.00002885221,0.002612524,0.001661232,0.06716965,0.000001369992,0.0004425793,0.005881585],"study_design_scores_gemma":[0.4023526,0.0007336237,0.5798332,0.0009090183,0.001024614,0.00004783994,0.0003931411,0.0126342,0.001818773,9.100073e-7,0.00004187217,0.0002101559],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930569,0.0001120406,0.00005274951,0.003067714,0.0003548718,0.003127705,0.00005188373,0.00007681886,0.00009931046],"genre_scores_gemma":[0.9961875,0.001729869,0.0009590845,0.0001537547,0.0003137903,0.0002433229,0.00002637424,0.00007556782,0.0003107571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3398643,"threshold_uncertainty_score":0.9999935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05243481214448267,"score_gpt":0.2879107943886995,"score_spread":0.2354759822442169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}