{"id":"W4315702471","doi":"10.1021/acsami.2c19311","title":"Elimination of Cancer Cells in Co-Culture: Role of Different Nanocarriers in Regulation of CD47 and Calreticulin-Induced Phagocytosis","year":2023,"lang":"en","type":"article","venue":"ACS Applied Materials & Interfaces","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; University of Toronto; National Research Council Canada","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"CD47; Phagocytosis; Calreticulin; Gene knockdown; Cancer cell; Cancer research; Small interfering RNA; Cell biology; Cell culture; Materials science; Biology; Cancer; Apoptosis; Chemistry; Transfection; Biochemistry; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002979266,0.000142348,0.0005054138,0.0002075129,0.00002046289,0.000006607691,0.0001086777,0.0002035494,0.0001055873],"category_scores_gemma":[0.00001738296,0.0001187302,0.00001619494,0.0001702504,0.0001164684,0.00006206784,0.00006192322,0.00005853405,0.000004763039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004018325,"about_ca_system_score_gemma":0.00001690304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003581449,"about_ca_topic_score_gemma":0.00008266811,"domain_scores_codex":[0.9987632,0.0001143789,0.0007063365,0.0002022714,0.00005693833,0.0001568811],"domain_scores_gemma":[0.9993019,0.00005697343,0.0004374032,0.0001459724,0.00005081169,0.000006914913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003304051,0.00006274919,0.0008585152,0.0001092643,0.00004732543,6.056077e-8,0.002753151,0.00005203176,0.9926721,0.0005227879,0.00002522303,0.00256641],"study_design_scores_gemma":[0.0009085971,0.00009153566,0.08105867,0.0001184674,0.00002464791,3.112267e-7,0.0009215592,0.000003624982,0.9164613,0.0003110193,0.00001006633,0.0000901551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987877,0.0005076552,7.578633e-7,0.00002854893,0.0001788645,0.0003311599,0.00008729472,0.00001105551,0.00006698308],"genre_scores_gemma":[0.999405,0.0003711075,0.000006837716,0.000003710898,0.000005982243,0.00005378748,0.0001100698,0.00001100942,0.00003255483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08020015,"threshold_uncertainty_score":0.4841678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009900771519843558,"score_gpt":0.2577276973329727,"score_spread":0.2478269258131292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}