{"id":"W4315710112","doi":"10.1097/01.hjh.0000917476.58907.17","title":"PS-B11-8: ONE NOVEL MIRNA WITH 4 MRNA TARGETS WAS IDENTIFIED IN PERIPHERAL BLOOD MONONUCLEAR CELLS OF HYPERTENSIVE PATIENTS WITH METABOLIC SYNDROME","year":2023,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University; Centre Hospitalier Universitaire Sainte-Justine; Jewish General Hospital","funders":"","keywords":"Peripheral blood mononuclear cell; microRNA; Immune system; Medicine; Fold change; Messenger RNA; RNA; Kidney disease; Metabolic syndrome; Blood pressure; Gene isoform; Immunology; Transcriptome; Internal medicine; Endocrinology; Gene expression; Gene; Biology; Diabetes mellitus; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001300629,0.0002788853,0.0004001714,0.0003535107,0.0002900107,0.0003617292,0.0001012848,0.0003324809,0.001996967],"category_scores_gemma":[0.0003786816,0.0001590765,0.0002580652,0.000298876,0.0001594994,0.0001254126,0.0001944032,0.000290927,0.0004402484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001287829,"about_ca_system_score_gemma":0.000142446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005082132,"about_ca_topic_score_gemma":0.000733134,"domain_scores_codex":[0.9998304,0.00001735947,0.00001677695,0.00007708073,0.00003458677,0.00002381806],"domain_scores_gemma":[0.9998399,0.00004051474,0.00004646716,0.00001070041,0.00002803279,0.00003435985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005684387,0.0001727697,0.2446757,0.0003838865,0.0003005591,0.002355401,0.0006272063,0.000332159,0.7138696,0.0001786575,0.001099156,0.03032044],"study_design_scores_gemma":[0.0001594899,0.001205428,0.9237613,0.00004689115,0.0004433825,0.00617617,0.0004679477,0.002263739,0.05820423,0.0003617168,0.006866993,0.00004266427],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953343,0.0009355811,0.001261049,0.00007769988,0.00003383407,0.00001802341,0.001470448,0.00003345938,0.000835572],"genre_scores_gemma":[0.9962191,0.0002544026,0.001350976,0.000111461,0.0000252887,0.00003751437,0.0008599623,0.0000183355,0.001122955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001996967,"threshold_uncertainty_score":0.006680489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0117658986335518,"score_gpt":0.1985111864784966,"score_spread":0.1867452878449448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}