{"id":"W4315754001","doi":"10.1097/hep.0000000000000045","title":"Checkpoint inhibitor hepatotoxicity: pathogenesis and management","year":2023,"lang":"en","type":"review","venue":"Hepatology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Toronto Liver Centre; University Health Network","funders":"","keywords":"Pathogenesis; Medicine; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004555339,0.0004444825,0.0005834033,0.001040776,0.0002768732,0.0008203256,0.0004496828,0.0007763266,0.001030606],"category_scores_gemma":[0.000966043,0.000129145,0.0004401439,0.0005975577,0.0003539213,0.0008844925,0.0005421035,0.001440787,0.0003876784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006948208,"about_ca_system_score_gemma":0.0008348297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000642536,"about_ca_topic_score_gemma":0.001095094,"domain_scores_codex":[0.999768,0.0000525593,0.0000602454,0.00003269119,0.00006166802,0.00002501337],"domain_scores_gemma":[0.9996935,0.00009619918,0.00009779483,0.000009212817,0.00006718405,0.00003600327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002451738,0.00009249266,0.007903519,0.008096175,0.000162163,0.004857542,0.0001924357,0.001134331,0.003099282,0.006039766,0.03101954,0.9371576],"study_design_scores_gemma":[0.000137089,0.0005924351,0.01985252,0.01355831,0.0006684347,0.1068233,0.0006931401,0.002461889,0.004978911,0.0179055,0.8322226,0.0001056864],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003108418,0.9889554,0.001432112,0.003308025,0.0002632344,0.00002342746,0.00004749219,0.00005059082,0.002811124],"genre_scores_gemma":[0.03375346,0.958702,0.002184831,0.002174382,0.001776213,0.00003558863,0.0001982039,0.00001268959,0.001162684],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001040776,"threshold_uncertainty_score":0.005041361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07329655356148833,"score_gpt":0.3506948007920936,"score_spread":0.2773982472306052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}