{"id":"W4315754322","doi":"10.1126/sciadv.abq6480","title":"Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement","year":2023,"lang":"en","type":"article","venue":"Science Advances","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; University of California, Irvine; National Institute of General Medical Sciences; Radboud Universiteit; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Cytokinesis; RHOA; Cell biology; Adherens junction; Live cell imaging; Cell; Chemistry; Microtubule; Biology; Cell division; Cadherin; Signal transduction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007476298,0.0002175876,0.0002101691,0.0001010447,0.0002383625,0.0003488968,0.0001627712,0.00016634,0.0004776259],"category_scores_gemma":[0.0001166856,0.0001871589,0.0001455995,0.00006013555,0.0003155082,0.0002227757,0.0003239522,0.000252577,0.0001470106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003957306,"about_ca_system_score_gemma":0.0002311989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005799881,"about_ca_topic_score_gemma":0.000922323,"domain_scores_codex":[0.9999257,0.000004725771,0.000002873551,0.0000227765,0.00002063337,0.00002324257],"domain_scores_gemma":[0.9999177,0.0000127235,0.00003261618,0.000007816811,0.000008854314,0.00002017818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001580681,0.000006141728,0.0001409527,0.000009432879,0.000001776745,0.0000421742,0.00001695763,0.0005533286,0.9978014,0.0007332657,0.00002382958,0.0006549484],"study_design_scores_gemma":[0.00001436462,0.00006560215,0.00200406,0.000002884406,0.000006688356,0.00009297742,0.00002740691,0.02058126,0.9751444,0.0004025473,0.001651527,0.000006106811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807742,0.0004306349,0.01693502,0.0001020943,0.00001598589,0.00001206241,0.0000334432,0.00009668899,0.001599767],"genre_scores_gemma":[0.9975327,0.0001334004,0.001527453,0.00001443947,0.000006190711,0.00001173372,0.00002144902,0.000005813456,0.0007468071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005799881,"threshold_uncertainty_score":0.002871215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007926135103297729,"score_gpt":0.2670478770468184,"score_spread":0.2591217419435207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}