{"id":"W4315767657","doi":"10.1021/acs.jcim.2c01116","title":"Structural and Energetic Features of Base–Base Stacking Contacts in RNA","year":2023,"lang":"en","type":"article","venue":"Journal of Chemical Information and Modeling","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; University Grants Commission; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Stacking; RNA; Nucleobase; Chemical physics; Crystallography; Macromolecule; Chemistry; Nanotechnology; Materials science; DNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002340397,0.00005830865,0.0001143307,0.00008076894,0.00001487409,0.00001814742,0.00004408445,0.00007087387,0.000002189228],"category_scores_gemma":[0.0001226286,0.00004733764,0.000030577,0.00004495492,0.00001366101,0.00003127591,0.00003214523,0.00006783455,1.401686e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004754198,"about_ca_system_score_gemma":0.00002454778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005239689,"about_ca_topic_score_gemma":7.511777e-7,"domain_scores_codex":[0.9994527,0.00001348311,0.0003147164,0.00004038421,0.00009755037,0.00008114787],"domain_scores_gemma":[0.999671,0.000012584,0.0001451564,0.00004253912,0.00007775093,0.00005093618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008750327,0.000002226762,0.00005416165,0.00003958464,0.000009027534,8.868072e-7,0.0001924343,0.002193288,0.9882038,0.0001008378,0.00003147169,0.009084842],"study_design_scores_gemma":[0.0005207367,0.00005331319,0.00006291681,0.00007018344,0.000007189676,0.00002750842,0.0002617188,0.02933625,0.9690732,0.0004409242,0.00007992398,0.00006611668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977356,0.0003289462,0.001690526,0.0001016573,0.00003716622,0.00003414977,0.000002805832,0.000001939363,0.00006718729],"genre_scores_gemma":[0.9985998,0.0002969403,0.0009485213,0.00009984898,0.00003659436,7.396235e-7,0.00001045691,0.000003066848,0.000004063085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02714296,"threshold_uncertainty_score":0.1930373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01875189073521604,"score_gpt":0.2547209988669321,"score_spread":0.2359691081317161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}